Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MYB_HUMAN
Description:v-myb myeloblastosis viral oncogene homolog (avian) [Source:HGNC Symbol;Acc:7545]
Location:chr6 q23.3
Node attribute:gene; substrate; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S11RHSIYsSDEDDCK2_alphaphosphoELM
T420EMPSLtSTPLICmyb_CPhosphoSitePlus
T534EVESPtDKSGNCmyb_CPhosphoSitePlus
S463SILESsPRTPTCmyb_CPhosphoSitePlus
S12HSIYSsDEDDECK2a1-rsRegPhos
S11RHSIYsSDEDDCK2a1-rsRegPhos
S11RHSIYsSDEDDCK2_groupphosphoELM; RegPhos
S12HSIYSsDEDDECK2_alphaphosphoELM
T433KLTVTtPFHRDCmyb_CPhosphoSitePlus
T466ESSPRtPTPFKCmyb_CPhosphoSitePlus
Y69KVIANyLPNRTMyb_DNA-bind_6PhosphoSitePlus
S532KQEVEsPTDKSErk2RegPhos
S532KQEVEsPTDKSCmyb_CPhosphoSitePlus
S11RHSIYsSDEDDCSNK2A1HPRD
S11RHSIYsSDEDDCK2a1RegPhos
S12HSIYSsDEDDECSNK2A1HPRD
S12HSIYSsDEDDECK2a1RegPhos
S532KQEVEsPTDKSMAPK_groupphosphoELM; RegPhos
S12HSIYSsDEDDECK2a1(CK2 alphaRegPhos
S12HSIYSsDEDDECK2_groupphosphoELM; RegPhos
S11RHSIYsSDEDDPhosphoSitePlus
S532KQEVEsPTDKSMAPK1HPRD
S532KQEVEsPTDKSMAPK3phosphoELM
S11RHSIYsSDEDDCK2a1(CK2 alphaRegPhos
S12HSIYSsDEDDEPhosphoSitePlus
S532KQEVEsPTDKSErk1(MAPK3RegPhos

Dephosphorylation site
MYB_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000339992E201*BIOMARTBreast Cancer21930507, 21930502
ENSP00000410825E514QTCGAOvarian Cancer21720365, 18772890
ENSP00000356788D334NCOSMICSkin Cancer21984974
ENSP00000356786*667YCOSMICOvarian Cancer21720365
ENSP00000356788E201*BIOMARTBreast Cancer21930507, 21930502
ENSP00000410825E201*BIOMARTBreast Cancer21930507, 21930502
ENSP00000356788E514QCOSMICOvarian Cancer21720365
ENSP00000356788C130YDing2008, COSMICLung Cancer18948947
ENSP00000339992E437*Ding2008, BIOMARTLung Cancer18948947, 21930507, 21930502

Differential expressed protein
MYB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MYB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK01_HUMANMYB_HUMANkinase -> substrateHPRD
CSK21_HUMANMYB_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
MK03_HUMANMYB_HUMANkinase -> substrateRobert H Newman (2013)
MZF1_HUMANMYB_HUMANTF -> target geneTRANSFAC
MYB_HUMANCDK1_HUMANTF -> target geneTRANSFAC
MYB_HUMANMYB_HUMANTF -> target geneTRANSFAC
MYB_HUMANKIT_HUMANTF -> target geneTRANSFAC
MYB_HUMANSRSF2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05166HTLV-I infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000082G1/S transition of mitotic cell cycleIEAbiological_process
GO:0051574positive regulation of histone H3-K9 methylationIMPbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0000122negative regulation of transcription from RNA polyIMPbiological_process
GO:0048566embryonic digestive tract developmentIEAbiological_process
GO:0048538thymus developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0045624positive regulation of T-helper cell differentiatiIMPbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0006338chromatin remodelingIMPbiological_process
GO:0003682chromatin bindingIEAmolecular_function
GO:0016363nuclear matrixNAScellular_component
GO:0051571positive regulation of histone H3-K4 methylationIMPbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0010468regulation of gene expressionIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0006816calcium ion transportIEAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0030183B cell differentiationIEAbiological_process
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIMPbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0048872homeostasis of number of cellsIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIMPbiological_process
GO:0006355regulation of transcription, DNA-dependentNASbiological_process


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