Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SRSF2_HUMAN
Description:serine/arginine-rich splicing factor 2 [Source:HGNC Symbol;Acc:10783]
Location:chr17 q25.1
Node attribute:substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S145SRSRYsRSKSRPhosphoSitePlus
S175KSKSSsVSRSRPhosphoSitePlus
S101PDSHHsRRGPPPhosphoSitePlus; HPRD; phosphoELM
S2____MsYGRPPPhosphoSitePlus
T29RTSPDtLRRVFRRM_1PhosphoSitePlus
T22KVDNLtYRTSPHPRD
Y23VDNLTyRTSPDRRM_1PhosphoSitePlus
S221EGAVSs_____PhosphoSitePlus
S208RSRSKsPPKSPPhosphoSitePlus; HPRD; phosphoELM
S173RSKSKsSSVSRPhosphoSitePlus
S196SPPPVsKRESKPhosphoSitePlus; HPRD
Y44RVGDVyIPRDRRRM_1PhosphoSitePlus
S220EEGAVsS____PhosphoSitePlus
S26LTYRTsPDTLRHPRD; phosphoELM
S189RSRSRsRSPPPPhosphoSitePlus; HPRD; phosphoELM
T29RTSPDtLRRVFHPRD
S187RSRSRsRSRSPPhosphoSitePlus; HPRD
S221EGAVHPRD; phosphoELM
Y144RSRSRySRSKSPhosphoSitePlus
T25NLTYRtSPDTLRRM_1PhosphoSitePlus
S204ESKSRsRSKSPPhosphoSitePlus; HPRD; phosphoELM
S191RSRSRsPPPVSPhosphoSitePlus; HPRD; phosphoELM
S206KSRSRsKSPPKPhosphoSitePlus; HPRD; phosphoELM
S212KSPPKsPEEEGPhosphoSitePlus; HPRD; phosphoELM
S2GRPPHPRD
Y115YGGGGyGRRSRPhosphoSitePlus
T25NLTYRtSPDTLHPRD; phosphoELM
S142RSRSRsRYSRSPhosphoSitePlus
T22KVDNLtYRTSPRRM_1PhosphoSitePlus
S220EEGAVHPRD; phosphoELM
S169RSARRsKSKSSPhosphoSitePlus
S26LTYRTsPDTLRRRM_1PhosphoSitePlus
Y23VDNLTyRTSPDHPRD; phosphoELM

Dephosphorylation site
SRSF2_HUMAN do not have dephosphorylation site.

Mutation site
SRSF2_HUMAN do not have mutation site.

Differential expressed protein
SRSF2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SRSF2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ST17A_HUMANSRSF2_HUMANkinase -> substrateRobert H Newman (2013)
CLK1_HUMANSRSF2_HUMANkinase -> substrateRobert H Newman (2013)
CLK2_HUMANSRSF2_HUMANkinase -> substrateRobert H Newman (2013)
SRPK2_HUMANSRSF2_HUMANkinase -> substrateRobert H Newman (2013)
KPCI_HUMANSRSF2_HUMANkinase -> substrateRobert H Newman (2013)
MYB_HUMANSRSF2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
SRSF2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000166nucleotide bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0031124mRNA 3'-end processingTASbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0003714transcription corepressor activityNASmolecular_function
GO:0006369termination of RNA polymerase II transcriptionTASbiological_process
GO:0010467gene expressionTASbiological_process
GO:0000398mRNA splicing, via spliceosomeTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0005681spliceosomal complexIEAcellular_component
GO:0016607nuclear speckIEAcellular_component
GO:0006397mRNA processingTASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0006406mRNA export from nucleusTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0016607nuclear speckIDAcellular_component
GO:0008380RNA splicingTASbiological_process


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