Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IFNA1_HUMAN
Description:interferon, alpha 1 [Source:HGNC Symbol;Acc:5417]
Location:chr9 p21.3
Node attribute:gene

Phosphorylation site
IFNA1_HUMAN do not have phosphorylation site.

Dephosphorylation site
IFNA1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000276927D25GCOSMICOvarian Cancer21720365
ENSP00000276927D25GTCGAOvarian Cancer21720365, 18772890
ENSP00000276927R148GCOSMICOvarian Cancer21720365
ENSP00000276927R148GTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
IFNA1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IFNA1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IRF7_HUMANIFNA1_HUMANTF -> target geneKEGG
IRF7_HUMANIFNA1_HUMANTF -> target geneTRANSFAC
IRF1_HUMANIFNA1_HUMANTF -> target geneTRANSFAC
IRF3_HUMANIFNA1_HUMANTF -> target geneTRANSFAC
IRF5_HUMANIFNA1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04622RIG-I-like receptor signaling pathway
hsa05162Measles
hsa05320Autoimmune thyroid disease
hsa05152Tuberculosis
hsa04620Toll-like receptor signaling pathway
hsa04650Natural killer cell mediated cytotoxicity
hsa04140Regulation of autophagy
hsa05168Herpes simplex infection
hsa04623Cytosolic DNA-sensing pathway
hsa04060Cytokine-cytokine receptor interaction
hsa05164Influenza A
hsa04630Jak-STAT signaling pathway
hsa05160Hepatitis C

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005125cytokine activityIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0045087innate immune responseTASbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0051607defense response to virusIEAbiological_process
GO:0005126cytokine receptor bindingIEAmolecular_function
GO:0060337type I interferon-mediated signaling pathwayTASbiological_process
GO:0060338regulation of type I interferon-mediated signalingTASbiological_process
GO:0006952defense responseIEAbiological_process
GO:0005132interferon-alpha/beta receptor bindingTASmolecular_function


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