| UniProt/SwissProt ID: | GPR12_HUMAN |
| Description: | G protein-coupled receptor 12 [Source:HGNC Symbol;Acc:4466] |
| Location: | chr13 q12.13 |
| Node attribute: | GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y243 | LATSHyVTTRK | 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| GPR12_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000370844 | P175L | COSMIC | Skin Cancer | 21984974 | ENSP00000370844 | G96E | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| GPR12_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GPR12_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GPR12_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| GPR12_HUMAN | GNAS2_HUMAN | GPCR -> Gprotein | gpDB |
| GPR12_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| GPR12_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| GPR12_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| GPR12_HUMAN | GNAS1_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| GPR12_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0031210 | phosphatidylcholine binding | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0006874 | cellular calcium ion homeostasis | IEA | biological_process |