Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FZD10_HUMAN
Description:frizzled family receptor 10 [Source:HGNC Symbol;Acc:4039]
Location:chr12 q24.33
Node attribute:PPI(source); PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S155APNNGsDEPTRPhosphoSitePlus
T159GSDEPtRGSGLPhosphoSitePlus
Y145KNDPNyLCMEAFzPhosphoSitePlus

Dephosphorylation site
FZD10_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000229030G339DCOSMICLung Cancer20668451
ENSP00000229030W9CCOSMICCentral Nervous System Neoplasms18772396
ENSP00000229030W326CCOSMICBreast Cancer20668451

Differential expressed protein
FZD10_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FZD10_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
WIF1_HUMANFZD10_HUMANotherKEGG
WNT11_HUMANFZD10_HUMANotherKEGG
FZD10_HUMANPLCB1_HUMANotherKEGG
WNT5A_HUMANFZD10_HUMANotherKEGG
CER1_HUMANFZD10_HUMANotherKEGG
SFRP1_HUMANFZD10_HUMANotherKEGG
FZD10_HUMANDVL1_HUMANotherKEGG
PORCN_HUMANFZD10_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04916Melanogenesis
hsa04310Wnt signaling pathway
hsa05166HTLV-I infection
hsa05217Basal cell carcinoma
hsa05200Pathways in cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0017147Wnt-protein bindingIEAmolecular_function
GO:0034259negative regulation of Rho GTPase activityIMPbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0030165PDZ domain bindingIBAmolecular_function
GO:0032956regulation of actin cytoskeleton organizationIMPbiological_process
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0017147Wnt-protein bindingIBAmolecular_function
GO:0005886plasma membraneIBAcellular_component
GO:0008406gonad developmentIBAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0001944vasculature developmentIBAbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0071300cellular response to retinoic acidISSbiological_process
GO:0042995cell projectionIBAcellular_component
GO:0043507positive regulation of JUN kinase activityIMPbiological_process
GO:0009790embryo developmentIBAbiological_process
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0004888transmembrane signaling receptor activityIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0038031non-canonical Wnt receptor signaling pathway via JIMPbiological_process
GO:0060070canonical Wnt receptor signaling pathwayIBAbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0007420brain developmentIBAbiological_process
GO:0032855positive regulation of Rac GTPase activityIMPbiological_process
GO:0030182neuron differentiationISSbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23