Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PORCN_HUMAN
Description:porcupine homolog (Drosophila) [Source:HGNC Symbol;Acc:17652]
Location:chrX p11.23
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S93LCRHSsHRGVFDUF3311; MBOATPhosphoSitePlus
S100RGVFLsVTILIMBOAT; TMPhosphoSitePlus
S92FLCRHsSHRGVDUF3311; MBOATPhosphoSitePlus

Dephosphorylation site
PORCN_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000322304A329TCOSMICOvarian Cancer21720365
ENSP00000322304L47WCOSMICOvarian Cancer21720365
ENSP00000354978G418SBIOMARTNeoplasms by Histologic Type21930507, 21930502
ENSP00000354978A324TTCGAOvarian Cancer21720365, 18772890
ENSP00000354978A318TTCGAOvarian Cancer21720365, 18772890
ENSP00000446401A329TCOSMICOvarian Cancer21720365
ENSP00000354978L47WTCGAOvarian Cancer21720365, 18772890
ENSP00000446401L47WCOSMICOvarian Cancer21720365
ENSP00000446401G429SCOSMICCentral Nervous System Neoplasms
ENSP00000322304G429SCOSMICCentral Nervous System Neoplasms
ENSP00000446401G147fs*39COSMICHead and Neck Cancer21798893
ENSP00000322304G147fs*39COSMICHead and Neck Cancer21798893

Differential expressed protein
PORCN_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PORCN_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PORCN_HUMANJAK1_HUMANotherKEGG
PORCN_HUMANFZD10_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04310Wnt signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0016746transferase activity, transferring acyl groupsIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0030176integral to endoplasmic reticulum membraneIEAcellular_component
GO:0009100glycoprotein metabolic processIEAbiological_process
GO:0016740transferase activityIEAmolecular_function


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