Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CHP1_HUMAN
Description:calcineurin-like EF-hand protein 1 [Source:HGNC Symbol;Acc:17433]
Location:chr15 q15.1
Node attribute:phosphotase; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S154DEQLGsIADRTPhosphoSitePlus
S26TGFSHsQITRLPhosphoSitePlus
S37YSRFTsLDKGEPhosphoSitePlus

Dephosphorylation site
CHP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000335632A156TCOSMICOvarian Cancer21720365

Differential expressed protein
CHP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CHP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CHP1_HUMANNFAC2_HUMANphosphatase -> substrateKEGG
CHP1_HUMANBAD_HUMANphosphatase -> substrateKEGG
CHP1_HUMANNFAT5_HUMANphosphatase -> substrateKEGG
CHP1_HUMANNFAC4_HUMANphosphatase -> substrateKEGG
PLCG1_HUMANCHP1_HUMANotherKEGG
CALL6_HUMANCHP1_HUMANotherKEGG
PLCB1_HUMANCHP1_HUMANotherKEGG
SODC_HUMANCHP1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04360Axon guidance
hsa04310Wnt signaling pathway
hsa04650Natural killer cell mediated cytotoxicity
hsa05031Amphetamine addiction
hsa04020Calcium signaling pathway
hsa04720Long-term potentiation
hsa05152Tuberculosis
hsa04660T cell receptor signaling pathway
hsa04114Oocyte meiosis
hsa04380Osteoclast differentiation
hsa04210Apoptosis
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa04010MAPK signaling pathway
hsa04724Glutamatergic synapse
hsa05166HTLV-I infection
hsa04370VEGF signaling pathway
hsa05010Alzheimer's disease
hsa04662B cell receptor signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060050positive regulation of protein glycosylationISSbiological_process
GO:0006611protein export from nucleusISSbiological_process
GO:0051453regulation of intracellular pHIDAbiological_process
GO:0005215transporter activityIEAmolecular_function
GO:0008017microtubule bindingIEAmolecular_function
GO:0051259protein oligomerizationIEAbiological_process
GO:0061025membrane fusionISSbiological_process
GO:0001578microtubule bundle formationIEAbiological_process
GO:0008017microtubule bindingISSmolecular_function
GO:0005737cytoplasmISScellular_component
GO:0001933negative regulation of protein phosphorylationISSbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0032088negative regulation of NF-kappaB transcription facIDAbiological_process
GO:0030133transport vesicleISScellular_component
GO:0015630microtubule cytoskeletonIEAcellular_component
GO:0031397negative regulation of protein ubiquitinationIEAbiological_process
GO:0048306calcium-dependent protein bindingIDAmolecular_function
GO:0031397negative regulation of protein ubiquitinationISSbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005215transporter activityISSmolecular_function
GO:0017156calcium ion-dependent exocytosisIEAbiological_process
GO:0031953negative regulation of protein autophosphorylationIEAbiological_process
GO:0032417positive regulation of sodium:hydrogen antiporter ISSbiological_process
GO:0005783endoplasmic reticulumISScellular_component
GO:0019900kinase bindingIEAmolecular_function
GO:0005793endoplasmic reticulum-Golgi intermediate compartmeIEAcellular_component
GO:0015459potassium channel regulator activityTASmolecular_function
GO:0030133transport vesicleIEAcellular_component
GO:0015630microtubule cytoskeletonISScellular_component
GO:0051222positive regulation of protein transportIEAbiological_process
GO:0001933negative regulation of protein phosphorylationIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005509calcium ion bindingIDAmolecular_function
GO:0031122cytoplasmic microtubule organizationIEAbiological_process
GO:0022406membrane dockingISSbiological_process
GO:0031122cytoplasmic microtubule organizationISSbiological_process
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0005829cytosolIEAcellular_component
GO:0060050positive regulation of protein glycosylationIEAbiological_process
GO:0061024membrane organizationIEAbiological_process
GO:0061025membrane fusionIEAbiological_process
GO:0071468cellular response to acidityISSbiological_process
GO:0061024membrane organizationISSbiological_process
GO:0050821protein stabilizationISSbiological_process
GO:0004860protein kinase inhibitor activityIEAmolecular_function
GO:0000139Golgi membraneISScellular_component
GO:0022406membrane dockingIEAbiological_process
GO:0045056transcytosisIEAbiological_process
GO:0006813potassium ion transportTASbiological_process
GO:0051222positive regulation of protein transportISSbiological_process
GO:0006469negative regulation of protein kinase activityIEAbiological_process
GO:0000139Golgi membraneIEAcellular_component
GO:0005634nucleusISScellular_component
GO:0042308negative regulation of protein import into nucleusIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0006611protein export from nucleusIEAbiological_process
GO:0070885negative regulation of calcineurin-NFAT signaling IDAbiological_process
GO:0019900kinase bindingISSmolecular_function
GO:0031953negative regulation of protein autophosphorylationISSbiological_process
GO:0007264small GTPase mediated signal transductionTASbiological_process
GO:0001578microtubule bundle formationISSbiological_process
GO:0090314positive regulation of protein targeting to membraISSbiological_process
GO:0005509calcium ion bindingIEAmolecular_function
GO:0005886plasma membraneIDAcellular_component
GO:0006469negative regulation of protein kinase activityISSbiological_process
GO:0010923negative regulation of phosphatase activityIDAbiological_process