| UniProt/SwissProt ID: | CCR9_HUMAN |
| Description: | chemokine (C-C motif) receptor 9 [Source:HGNC Symbol;Acc:1610] |
| Location: | chr3 p21.31 |
| Node attribute: | GPCR; receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T81 | CTRVKtMTDMF | 7tm_1 | PhosphoSitePlus |
| Y145 | ISVDRyIAIAQ | 7tm_1; TM | PhosphoSitePlus |
| S368 | TSGALsL____ | PhosphoSitePlus | |
| T83 | RVKTMtDMFLL | 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| CCR9_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000350256 | R323I | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| CCR9_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CCR9_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CCL25_HUMAN | CCR9_HUMAN | ligand -> receptor | HPMR |
| CCR9_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| CCR9_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| CCR9_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| CCR9_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| CCL25_HUMAN | CCR9_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04062 | Chemokine signaling pathway |
| hsa04672 | Intestinal immune network for IgA production |
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004950 | chemokine receptor activity | TAS | molecular_function |
| GO:0016493 | C-C chemokine receptor activity | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0070098 | chemokine-mediated signaling pathway | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0007204 | elevation of cytosolic calcium ion concentration | TAS | biological_process |
| GO:0006935 | chemotaxis | IEA | biological_process |
| GO:0006968 | cellular defense response | TAS | biological_process |