| UniProt/SwissProt ID: | CCL25_HUMAN |
| Description: | chemokine (C-C motif) ligand 25 [Source:HGNC Symbol;Acc:10624] |
| Location: | chr19 p13.2 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S135 | SNPISsSKRNV | PhosphoSitePlus | |
| S141 | SKRNVsLLISA | PhosphoSitePlus | |
| T104 | KLHHNtQTFQA | PhosphoSitePlus | |
| Dephosphorylation site |
| CCL25_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000375086 | A41T | COSMIC | Skin Cancer | 21984974 | ENSP00000253451 | *150L | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000253451 | G109R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000375086 | A109P | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| CCL25_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CCL25_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CCL25_HUMAN | CCR9_HUMAN | ligand -> receptor | HPMR |
| CCL25_HUMAN | CCR9_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04062 | Chemokine signaling pathway |
| hsa04672 | Intestinal immune network for IgA production |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0006955 | immune response | IEA | biological_process |
| GO:0007166 | cell surface receptor signaling pathway | TAS | biological_process |
| GO:0031735 | CCR10 chemokine receptor binding | IDA | molecular_function |
| GO:0005179 | hormone activity | TAS | molecular_function |
| GO:0008009 | chemokine activity | IEA | molecular_function |
| GO:0006954 | inflammatory response | IEA | biological_process |
| GO:0006935 | chemotaxis | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0050900 | leukocyte migration | IEA | biological_process |
| GO:0005615 | extracellular space | IEA | cellular_component |