Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:B2L11_HUMAN
Description:BCL2-like 11 (apoptosis facilitator) [Source:HGNC Symbol;Acc:994]
Location:chr2 q13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S118STQTPsPPCQAMAPK8HPRD
S69LAPPAsPGPFAMAPK1phosphoELM
S94LSRSSsGYFSFPhosphoSitePlus
S104FDTDRsPAPMSMAPK8HPRD
S118STQTPsPPCQAPhosphoSitePlus
S69LAPPAsPGPFAMAPK3phosphoELM
S69LAPPAsPGPFAMAPK8HPRD
S69LAPPAsPGPFAMAPK9HPRD
S104FDTDRsPAPMSPhosphoSitePlus
S77PFATRsPLFIFMAPK9HPRD
S77PFATRsPLFIFMAPK8HPRD
S59SCPHGsPQGPLPhosphoSitePlus
T56DKSTQtPSPPCMAPK8HPRD
S59SCPHGsPQGPLMAPK10HPRD
S87FMRRSsLLSRSPhosphoSitePlus
S77PFATRsPLFIFPhosphoSitePlus; HPRD; phosphoELM
S104FDTDRsPAPMSJNK_groupphosphoELM
S59SCPHGsPQGPLMAPK9HPRD
T116DKSTQtPSPPCJNK_groupphosphoELM
S69LAPPAsPGPFAMAPK10HPRD
T116DKSTQtPSPPCMAPK8HPRD
S59SCPHGsPQGPLMAPK8HPRD
T116DKSTQtPSPPCPhosphoSitePlus
S58STQTPsPPCQAMAPK8HPRD
S69LAPPAsPGPFAPhosphoSitePlus
S118STQTPsPPCQAJNK_groupphosphoELM
S77PFATRsPLFIFMAPK10HPRD

Dephosphorylation site
B2L11_HUMAN do not have dephosphorylation site.

Mutation site
B2L11_HUMAN do not have mutation site.

Differential expressed protein
B2L11_HUMAN is not differential expressed protein.

Hyperphosphorylation site
B2L11_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK09_HUMANB2L11_HUMANkinase -> substrateRegPhos
MK10_HUMANB2L11_HUMANkinase -> substrateRegPhos
MK01_HUMANB2L11_HUMANkinase -> substrateRobert H Newman (2013)
MK03_HUMANB2L11_HUMANkinase -> substrateRobert H Newman (2013)
MK08_HUMANB2L11_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
B2L11_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0048538thymus developmentIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0002260lymphocyte homeostasisIEAbiological_process
GO:0097140BIM-BCL-xl complexIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0045787positive regulation of cell cycleIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0043583ear developmentIEAbiological_process
GO:0005741mitochondrial outer membraneTAScellular_component
GO:0001782B cell homeostasisIEAbiological_process
GO:0042475odontogenesis of dentin-containing toothIEAbiological_process
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0046620regulation of organ growthIEAbiological_process
GO:0007160cell-matrix adhesionIEAbiological_process
GO:0032464positive regulation of protein homooligomerizationIDAbiological_process
GO:0001776leukocyte homeostasisIEAbiological_process
GO:0060154cellular process regulating host cell cycle in resIEAbiological_process
GO:0006917induction of apoptosisIEAbiological_process
GO:0001822kidney developmentIEAbiological_process
GO:0048536spleen developmentIEAbiological_process
GO:0034976response to endoplasmic reticulum stressIEAbiological_process
GO:0006917induction of apoptosisTASbiological_process
GO:0002262myeloid cell homeostasisIEAbiological_process
GO:0048066developmental pigmentationIEAbiological_process
GO:0048070regulation of developmental pigmentationIEAbiological_process
GO:0007283spermatogenesisIEAbiological_process
GO:0035148tube formationIEAbiological_process
GO:2001244positive regulation of intrinsic apoptotic signaliIMPbiological_process
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0007420brain developmentIEAbiological_process
GO:0019898extrinsic to membraneIEAcellular_component
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0005739mitochondrionIEAcellular_component
GO:0009791post-embryonic developmentIEAbiological_process
GO:0006915apoptotic processTASbiological_process
GO:0005874microtubuleIDAcellular_component
GO:0043231intracellular membrane-bounded organelleIEAcellular_component
GO:0043525positive regulation of neuron apoptotic processIEAbiological_process
GO:0008017microtubule bindingIDAmolecular_function
GO:0043065positive regulation of apoptotic processIMPbiological_process
GO:0097141BIM-BCL-2 complexIDAcellular_component
GO:0043029T cell homeostasisIEAbiological_process
GO:0012505endomembrane systemIEAcellular_component
GO:0048563post-embryonic organ morphogenesisIEAbiological_process
GO:0006919activation of cysteine-type endopeptidase activityIDAbiological_process
GO:0008017microtubule bindingIEAmolecular_function
GO:0001783B cell apoptotic processIEAbiological_process
GO:0090200positive regulation of release of cytochrome c froIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0030879mammary gland developmentIEAbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0034976response to endoplasmic reticulum stressIDAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0008584male gonad developmentIEAbiological_process