Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ACM4_HUMAN
Description:cholinergic receptor, muscarinic 4 [Source:HGNC Symbol;Acc:1953]
Location:chr11 p11.2
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S296DTSNEsSSGSA7tm_1PhosphoSitePlus
T311KERPAtELSTT7tm_1PhosphoSitePlus
T292VADKDtSNESS7tm_1PhosphoSitePlus
S293ADKDTsNESSS7tm_1PhosphoSitePlus

Dephosphorylation site
ACM4_HUMAN do not have dephosphorylation site.

Mutation site
ACM4_HUMAN do not have mutation site.

Differential expressed protein
ACM4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ACM4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLAT_HUMANACM4_HUMANligand -> receptorHPMR
ACM4_HUMANGNAO_HUMANGPCR -> GproteingpDB
ACM4_HUMANGNAI2_HUMANGPCR -> GproteingpDB
ACM4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ACM4_HUMANGNAI1_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04725Cholinergic synapse
hsa04810Regulation of actin cytoskeleton
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007197adenylate cyclase-inhibiting G-protein coupled aceIEAbiological_process
GO:0008283cell proliferationTASbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0007213G-protein coupled acetylcholine receptor signalingTASbiological_process
GO:0007165signal transductionTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0016907G-protein coupled acetylcholine receptor activityIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0030054cell junctionIEAcellular_component
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0045211postsynaptic membraneIEAcellular_component


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