Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UB2L3_HUMAN
Description:ubiquitin-conjugating enzyme E2L 3 [Source:HGNC Symbol;Acc:12488]
Location:chr22 q11.21
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y129DLAEEySKDRKUQ_conPhosphoSitePlus
Y147EFTKKyGEKRPPhosphoSitePlus

Dephosphorylation site
UB2L3_HUMAN do not have dephosphorylation site.

Mutation site
UB2L3_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000344259Pancreatic CancerNormal vs. CancertissueUp33019199705

Hyperphosphorylation site
UB2L3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SLTM_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)
MAST2_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)
PXK_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)
M3K7_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)
FYN_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
UB2L3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031625ubiquitin protein ligase bindingIPImolecular_function
GO:0006355regulation of transcription, DNA-dependentIMPbiological_process
GO:0000151ubiquitin ligase complexTAScellular_component
GO:0007090regulation of S phase of mitotic cell cycleIMPbiological_process
GO:0000209protein polyubiquitinationIDAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0071385cellular response to glucocorticoid stimulusIDAbiological_process
GO:0003713transcription coactivator activityIDAmolecular_function
GO:0015031protein transportIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0006464cellular protein modification processTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0008283cell proliferationIMPbiological_process
GO:0006511ubiquitin-dependent protein catabolic processTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0016567protein ubiquitinationIDAbiological_process
GO:0019899enzyme bindingTASmolecular_function
GO:0004842ubiquitin-protein ligase activityIMPmolecular_function
GO:0070979protein K11-linked ubiquitinationIDAbiological_process
GO:0016881acid-amino acid ligase activityIEAmolecular_function
GO:0071383cellular response to steroid hormone stimulusIMPbiological_process


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