Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRAT1_HUMAN
Description:T cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:30698]
Location:chr3 q13.13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T103PSAQAtNETQMPhosphoSitePlus
Y110ETQMCyASLDHPhosphoSitePlus; HPRD
T129PRKQNtHFSDKPhosphoSitePlus
Y79MDENCyEQMKAPhosphoSitePlus
S112QMCYAsLDHSVPhosphoSitePlus
S46KMYSYsSDHTRPhosphoSitePlus
Y43RQDKMySYSSDPhosphoSitePlus
S132QNTHFsDKDGDPhosphoSitePlus
T106QATNEtQMCYAPhosphoSitePlus
S44QDKMYsYSSDHPhosphoSitePlus
S116ASLDHsVKGKRPhosphoSitePlus
S47MYSYSsDHTRVPhosphoSitePlus
Y45DKMYSySSDHTPhosphoSitePlus

Dephosphorylation site
TRAT1_HUMAN do not have dephosphorylation site.

Mutation site
TRAT1_HUMAN do not have mutation site.

Differential expressed protein
TRAT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRAT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BMX_HUMANTRAT1_HUMANkinase -> substrateRobert H Newman (2013)
ZAP70_HUMANTRAT1_HUMANkinase -> substrateRobert H Newman (2013)
FYN_HUMANTRAT1_HUMANkinase -> substrateNetPath
LCK_HUMANTRAT1_HUMANkinase -> substrateNetPath
AKT1_HUMANTRAT1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TRAT1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007169transmembrane receptor protein tyrosine kinase sigTASbiological_process
GO:0001920negative regulation of receptor recyclingIDAbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0050862positive regulation of T cell receptor signaling pIDAbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0050850positive regulation of calcium-mediated signalingIDAbiological_process
GO:0051051negative regulation of transportIDAbiological_process
GO:0042101T cell receptor complexIDAcellular_component
GO:0006968cellular defense responseTASbiological_process
GO:0007165signal transductionTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0005068transmembrane receptor protein tyrosine kinase adaTASmolecular_function


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