Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:T22D4_HUMAN
Description:TSC22 domain family, member 4 [Source:HGNC Symbol;Acc:21696]
Location:chr7 q22.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S187EKPPLsASSPQHPRD
S263LDSRPsSPALYPhosphoSitePlus
S370LRALAsPEQLATSC22PhosphoSitePlus; SysPTM
S165GPQARsFTGGLPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S233RTPPLsRRKAVPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S62TPRNGsPPPGAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S225AEAGGsGARTPPhosphoSitePlus; HPRD; phosphoELM
T167QARSFtGGLGQPhosphoSitePlus
T211TSRAAtPLPSLPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S279SLVHKsPDPFGPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y268SSPALyFTHDAHPRD; phosphoELM
S116GIRGAsGGAGGPhosphoSitePlus
T157LRPPPtSPGPQHPRD
T139GLGAPtPPSGLPhosphoSitePlus; HPRD
S177QLVVPsKAKAEPhosphoSitePlus
T270PALYFtHDASLHPRD; phosphoELM
S69PPGAPsSRFRVHPRD
S370LRALAsPEQLAHPRD; phosphoELM; SysPTM
S158RPPPTsPGPQAPhosphoSitePlus; HPRD
S70PGAPSsRFRVVHPRD
S132RLELAsLGLGAHPRD
T229GSGARtPPLSRPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T57PGGKGtPRNGSPhosphoSitePlus
S49PNGEPsPDPGGPhosphoSitePlus; HPRD

Dephosphorylation site
T22D4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000300181V329MSjoblom2006, COSMIC, HPIBreast Cancer16959974

Differential expressed protein
T22D4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
T22D4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ST17A_HUMANT22D4_HUMANkinase -> substrateRobert H Newman (2013)
KPCD_HUMANT22D4_HUMANkinase -> substrateRobert H Newman (2013)
CDK5_HUMANT22D4_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANT22D4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
T22D4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006970response to osmotic stressIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0006355regulation of transcription, DNA-dependentNASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process


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