| UniProt/SwissProt ID: | SPN1_HUMAN |
| Description: | snurportin 1 [Source:HGNC Symbol;Acc:14245] |
| Location: | chr15 q24.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S329 | LTHKAsENGHY | PhosphoSitePlus | |
| S340 | ELEHLsTPKLK | PhosphoSitePlus | |
| T341 | LEHLStPKLKG | PhosphoSitePlus | |
| S36 | YKSKYsSLEQS | IBB; Snurportin1 | PhosphoSitePlus |
| Y31 | PRLSQyKSKYS | IBB; Snurportin1 | PhosphoSitePlus |
| S347 | PKLKGsSHSPD | HPRD | |
| Y301 | TTKPDyAGHQL | PhosphoSitePlus | |
| Y334 | SENGHyELEHL | PhosphoSitePlus | |
| S75 | WTGMEsEEENK | HPRD | |
| S75 | WTGMEsEEENK | IBB | PhosphoSitePlus |
| S37 | KSKYSsLEQSE | IBB; Snurportin1 | PhosphoSitePlus |
| S350 | KGSSHsPDHPG | PhosphoSitePlus; HPRD; phosphoELM | |
| S29 | PHPRLsQYKSK | HPRD | |
| Y35 | QYKSKySSLEQ | IBB; Snurportin1 | PhosphoSitePlus |
| Dephosphorylation site |
| SPN1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000309831 | T21I | COSMIC | Pancreatic Cancer | |
| Differential expressed protein |
| SPN1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SPN1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK4_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST17A_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AAPK2_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| DYRK4_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK5_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCA_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| WEE1_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| HIPK1_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| TGFR2_HUMAN | SPN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| SPN1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0034660 | ncRNA metabolic process | TAS | biological_process |
| GO:0000339 | RNA cap binding | TAS | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005643 | nuclear pore | TAS | cellular_component |
| GO:0010467 | gene expression | TAS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0008565 | protein transporter activity | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0061015 | snRNA import into nucleus | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0006606 | protein import into nucleus | IEA | biological_process |
| GO:0000387 | spliceosomal snRNP assembly | TAS | biological_process |