Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SPIB_HUMAN
Description:Transcription factor Spi-B [Source:UniProtKB/Swiss-Prot;Acc:Q01892]
Location:chr19 q13.33
Node attribute:substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S146LEVSDsESDEACK2a1-rsRegPhos
S37SSYPDsEGAPDCK2a1-rsRegPhos
S146LEVSDsESDEACK2a2RegPhos
S37SSYPDsEGAPDCK2_groupphosphoELM; RegPhos
S144PALEVsDSESDCK2a1-rsRegPhos
S146LEVSDsESDEACK2a1RegPhos
S146LEVSDsESDEACK2_groupphosphoELM; RegPhos
S129PSPVLsEEEDLCK2a1-rsRegPhos
S144PALEVsDSESDCK2a2RegPhos
S144PALEVsDSESDCK2a1RegPhos
S37SSYPDsEGAPDCK2a1RegPhos
T56PPVPAtPYEAFErk1RegPhos
S37SSYPDsEGAPDCK2a2RegPhos
T56PPVPAtPYEAFMAPK3phosphoELM
S129PSPVLsEEEDLCK2a2RegPhos
S129PSPVLsEEEDLCK2a1RegPhos
T56PPVPAtPYEAFErk1(MAPK3RegPhos
S144PALEVsDSESDCK2_groupphosphoELM; RegPhos
S129PSPVLsEEEDLCK2_groupphosphoELM; RegPhos

Dephosphorylation site
SPIB_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000270632E162*COSMICRenal Cancer20054297

Differential expressed protein
SPIB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SPIB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK22_HUMANSPIB_HUMANkinase -> substrateHPRD
MK03_HUMANSPIB_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
CSK21_HUMANSPIB_HUMANkinase -> substrateHPRD
PRDM1_HUMANSPIB_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
SPIB_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006357regulation of transcription from RNA polymerase IITASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005737cytoplasmTAScellular_component
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0015630microtubule cytoskeletonIDAcellular_component
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process


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