Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SDF1_HUMAN
Description:chemokine (C-X-C motif) ligand 12 [Source:HGNC Symbol;Acc:10672]
Location:chr10 q11.21
Node attribute:ligand; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y28PVSLSyRCPCRIL8PhosphoSitePlus

Dephosphorylation site
SDF1_HUMAN do not have dephosphorylation site.

Mutation site
SDF1_HUMAN do not have mutation site.

Differential expressed protein
SDF1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SDF1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SDF1_HUMANCXCR4_HUMANligand -> receptorHPMR
SDF1_HUMANCXCR3_HUMANligand -> receptorHPMR
SDF1_HUMANCXCR7_HUMANotherKEGG
SDF1_HUMANCXCR4_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04064NF-kappa B signaling pathway
hsa04670Leukocyte transendothelial migration
hsa04672Intestinal immune network for IgA production
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa05323Rheumatoid arthritis
hsa04360Axon guidance

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008354germ cell migrationIEAbiological_process
GO:0006874cellular calcium ion homeostasisTASbiological_process
GO:0006955immune responseIEAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0042098T cell proliferationIEAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0007155cell adhesionTASbiological_process
GO:0030334regulation of cell migrationIEAbiological_process
GO:0008064regulation of actin polymerization or depolymerizaTASbiological_process
GO:0001667ameboidal cell migrationIEAbiological_process
GO:0008015blood circulationTASbiological_process
GO:0008009chemokine activityIEAmolecular_function
GO:0001569patterning of blood vesselsIEAbiological_process
GO:0090026positive regulation of monocyte chemotaxisIDAbiological_process
GO:0070098chemokine-mediated signaling pathwayIDAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007420brain developmentIEAbiological_process
GO:0008045motor neuron axon guidanceIEAbiological_process
GO:0006935chemotaxisTASbiological_process
GO:0030335positive regulation of cell migrationIEAbiological_process
GO:0050930induction of positive chemotaxisIEAbiological_process
GO:0045236CXCR chemokine receptor bindingIDAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0009615response to virusTASbiological_process
GO:0009897external side of plasma membraneIEAcellular_component
GO:0005615extracellular spaceIEAcellular_component
GO:0005102receptor bindingTASmolecular_function
GO:2000107negative regulation of leukocyte apoptotic processIDAbiological_process
GO:0007281germ cell developmentIEAbiological_process
GO:0043066negative regulation of apoptotic processIDAbiological_process


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