| UniProt/SwissProt ID: | CXCR7_HUMAN |
| Description: | chemokine (C-X-C motif) receptor 7 [Source:HGNC Symbol;Acc:23692] |
| Location: | chr2 q37.3 |
| Node attribute: | PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S335 | FIFKYsAKTGL | PhosphoSitePlus | |
| Y354 | VSETEySALEQ | PhosphoSitePlus | |
| S355 | SETEYsALEQS | PhosphoSitePlus | |
| Y334 | AFIFKySAKTG | PhosphoSitePlus | |
| T338 | KYSAKtGLTKL | PhosphoSitePlus | |
| S350 | DASRVsETEYS | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| CXCR7_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000272928 | Y45* | COSMIC | Intestines Cancer | 16959974 | ENSP00000272928 | S15L | COSMIC | Melanoma | ENSP00000272928 | Y45X | BIOMART | Colorectal Cancer | 21930507, 21930502 |
| Differential expressed protein |
| CXCR7_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CXCR7_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CXL11_HUMAN | CXCR7_HUMAN | other | KEGG |
| SDF1_HUMAN | CXCR7_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0070098 | chemokine-mediated signaling pathway | IMP | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0016021 | integral to membrane | NAS | cellular_component |
| GO:0019048 | virus-host interaction | IEA | biological_process |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0048471 | perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0055037 | recycling endosome | IEA | cellular_component |
| GO:0005769 | early endosome | IEA | cellular_component |
| GO:0043066 | negative regulation of apoptotic process | IMP | biological_process |
| GO:0016494 | C-X-C chemokine receptor activity | IMP | molecular_function |