| UniProt/SwissProt ID: | RSSA_HUMAN |
| Description: | ribosomal protein SA [Source:HGNC Symbol;Acc:6502] |
| Location: | chr3 p22.1 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T125 | RLLVVtDPRAD | HPRD | |
| Y139 | LTEASyVNLPT | Ribosomal_S2 | PhosphoSitePlus |
| S43 | IYKRKsDGIYI | HPRD; SysPTM | |
| T125 | RLLVVtDPRAD | Ribosomal_S2 | PhosphoSitePlus |
| Y204 | PDLYFyRDPEE | PhosphoSitePlus | |
| S43 | IYKRKsDGIYI | Ribosomal_S2 | PhosphoSitePlus; SysPTM |
| T241 | PEFTAtQPEVA | HPRD | |
| Y139 | LTEASyVNLPT | HPRD; phosphoELM | |
| Y156 | DSPLRyVDIAI | Ribosomal_S2 | PhosphoSitePlus |
| S2 | ____MsGALDV | PhosphoSitePlus | |
| S138 | PLTEAsYVNLP | Ribosomal_S2 | PhosphoSitePlus |
| Y39 | MEQYIyKRKSD | Ribosomal_S2 | PhosphoSitePlus |
| T135 | DHQPLtEASYV | Ribosomal_S2 | PhosphoSitePlus |
| Dephosphorylation site |
| RSSA_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000346067 | T232A | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000346067 | R102C | Ding2008, COSMIC | Lung Cancer | 18948947 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000346067 | Uterine Cancer | Normal vs. Cancer | tissue | Up | 17902640 | ENSP00000346067 | colorectal cancer | Normal vs. Cancer | tissue | Down | 0.47 | 15924290 | ENSP00000346067 | Hepatocellular Carcinoma | Normal vs. Cancer | tissue | Up | 4.1 | 15759316 | ENSP00000346067 | hepatitis B virus | Normal vs. Cancer | tissue | Up | 2.1 | 14654528 | ENSP00000346067 | Breast Cancer | Normal vs. Cancer | tissue | Up | >10 | 20005186 | ENSP00000346067 | acute myeloid leukemia | Treatment (none vs. NSC606985 treatment) | cell line | Up | 17655343 | ENSP00000346067 | acute myeloid leukemia | Treatment (none vs. NSC606985 treatment) | cell line | Down | 0.27 | 17655343 | ENSP00000346067 | acute myeloid leukemia | Treatment (none vs. NSC606985 treatment) | cell line | Up | 17655343 | ENSP00000346067 | Neoplasms by Histologic Type | Treatment (none vs. SB203580 treatment 21 hour) | cell line | Down | 0.5 | 15169874 | ENSP00000346067 | Gastric Cancer | Normal vs. Cancer | tissue | Up | 20677338 |
| Hyperphosphorylation site |
| RSSA_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DUS18_HUMAN | RSSA_HUMAN | ligand -> receptor | HPMR |
| LAMC1_HUMAN | RSSA_HUMAN | ligand -> receptor | HPMR |
| LAMA2_HUMAN | RSSA_HUMAN | ligand -> receptor | HPMR |
| LAMA1_HUMAN | RSSA_HUMAN | ligand -> receptor | HPMR |
| PRND_HUMAN | RSSA_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa03010 | Ribosome |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0019058 | viral infectious cycle | TAS | biological_process |
| GO:0006415 | translational termination | TAS | biological_process |
| GO:0006414 | translational elongation | TAS | biological_process |
| GO:0016071 | mRNA metabolic process | TAS | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0007155 | cell adhesion | NAS | biological_process |
| GO:0006413 | translational initiation | TAS | biological_process |
| GO:0030686 | 90S preribosome | IBA | cellular_component |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0016032 | viral reproduction | TAS | biological_process |
| GO:0015935 | small ribosomal subunit | IEA | cellular_component |
| GO:0006412 | translation | IEA | biological_process |
| GO:0006407 | rRNA export from nucleus | IBA | biological_process |
| GO:0019083 | viral transcription | TAS | biological_process |
| GO:0000461 | endonucleolytic cleavage to generate mature 3'-end | IBA | biological_process |
| GO:0022627 | cytosolic small ribosomal subunit | IDA | cellular_component |
| GO:0000028 | ribosomal small subunit assembly | IBA | biological_process |
| GO:0005737 | cytoplasm | TAS | cellular_component |
| GO:0006412 | translation | IC | biological_process |
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsen | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to | TAS | biological_process |
| GO:0044267 | cellular protein metabolic process | TAS | biological_process |
| GO:0003735 | structural constituent of ribosome | IBA | molecular_function |
| GO:0010467 | gene expression | TAS | biological_process |
| GO:0043022 | ribosome binding | IPI | molecular_function |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0003735 | structural constituent of ribosome | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005840 | ribosome | IEA | cellular_component |
| GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-r | IBA | biological_process |