| UniProt/SwissProt ID: | DUS18_HUMAN |
| Description: | dual specificity phosphatase 18 [Source:HGNC Symbol;Acc:18484] |
| Location: | chr22 q12.2 |
| Node attribute: | ligand |
| Phosphorylation site |
| DUS18_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| DUS18_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000386063 | R183C | COSMIC | Skin Cancer | 21984974 | ENSP00000366291 | R183C | COSMIC | Skin Cancer | 21984974 | ENSP00000333917 | R183C | COSMIC | Skin Cancer | 21984974 | ENSP00000385463 | R183C | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| DUS18_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| DUS18_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DUS18_HUMAN | RSSA_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| DUS18_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016791 | phosphatase activity | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0004725 | protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0035335 | peptidyl-tyrosine dephosphorylation | IDA | biological_process |
| GO:0008138 | protein tyrosine/serine/threonine phosphatase acti | IBA | molecular_function |
| GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase a | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0016311 | dephosphorylation | IEA | biological_process |
| GO:0006470 | protein dephosphorylation | IEA | biological_process |