Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PACS1_HUMAN
Description:phosphofurin acidic cluster sorting protein 1 [Source:HGNC Symbol;Acc:30032]
Location:chr11 q13.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S278DIDNYsEEEEECK2_groupphosphoELM; RegPhos
S113EVDRSsSSCVPPhosphoSitePlus
S411MSQSSsQTEIGPhosphoSitePlus
Y303GQDLFyEDEDLPhosphoSitePlus
S493TDLQGsASPSKPhosphoSitePlus; HPRD; phosphoELM
S112WEVDRsSSSCVPhosphoSitePlus
S278DIDNYsEEEEECK2a1-rsRegPhos
S381YNPSDsGPEMEHPRD; phosphoELM
S278DIDNYsEEEEECSNK2A1HPRD
S115DRSSSsCVPRLPhosphoSitePlus
S278DIDNYsEEEEECK2a1RegPhos
Y672HPVAKyLGSVDPacs-1PhosphoSitePlus
S28SGVAQsPQQPPPhosphoSitePlus; RegPhos
T319TRRKLtSTSAIPhosphoSitePlus
T46PPQQPtPPKLAPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S407FFEGMsQSSSQPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S322KLTSTsAITRQPhosphoSitePlus
S687SSFLDsGWRDLPacs-1PhosphoSitePlus
T504VEGVHtPRQKRPhosphoSitePlus; HPRD; phosphoELM
S651LANKTsDWLGYPacs-1PhosphoSitePlus
S495LQGSAsPSKVEPhosphoSitePlus; HPRD; phosphoELM
S252EIKIYsLSSQPPhosphoSitePlus
T526PLSERtNSSDSPhosphoSitePlus; HPRD
S410GMSQSsSQTEIPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S510PRQKRsTPLKEPhosphoSitePlus
T124RLFSLtLKKLVHPRD
T488MKSSKtDLQGSPhosphoSitePlus
S255IYSLSsQPIDHPhosphoSitePlus
Y370DLDELyDSLEMPhosphoSitePlus
S528SERTNsSDSERPhosphoSitePlus; HPRD; phosphoELM
S320RRKLTsTSAITPhosphoSitePlus
Y680SVDSKySSSFLPacs-1PhosphoSitePlus
S114VDRSSsSCVPRPhosphoSitePlus
Y613TRIQRyCNCNSPacs-1PhosphoSitePlus
S430GKDTTsPMELAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S497GSASPsKVEGVPhosphoSitePlus; HPRD; phosphoELM
S845KRDASsKNTLKPacs-1PhosphoSitePlus
Y549PRKVVyDQLNQPacs-1PhosphoSitePlus
S531TNSSDsERSPDPhosphoSitePlus; HPRD; phosphoELM
T413QSSSQtEIGSLPhosphoSitePlus
T511RQKRStPLKERPhosphoSitePlus
S529ERTNSsDSERSPhosphoSitePlus; HPRD; phosphoELM
T848ASSKNtLKSVFPacs-1PhosphoSitePlus
Y104VQMNLyATWEVPhosphoSitePlus
S534SDSERsPDLGHPhosphoSitePlus; HPRD; phosphoELM
S278DIDNYsEEEEEPhosphoSitePlus
S779SLTVPsTSPPSPacs-1PhosphoSitePlus
T429LGKDTtSPMELHPRD; RegPhos
S844DKRDAsSKNTLPacs-1PhosphoSitePlus
Y251AEIKIySLSSQPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S379EMYNPsDSGPEPhosphoSitePlus; HPRD; phosphoELM
T321RKLTStSAITRPhosphoSitePlus

Dephosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S278SPDIDNYsEEEEESFPPP2CBHPRD
S278SPDIDNYsEEEEESFPPP2CAHPRD

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000316454R203WCOSMICOvarian Cancer21720365
ENSP00000316454R709GTCGAOvarian Cancer21720365, 18772890
ENSP00000316454R709GCOSMICOvarian Cancer21720365
ENSP00000316454V602MTCGAOvarian Cancer21720365, 18772890
ENSP00000316454S59CCOSMICOvarian Cancer21720365
ENSP00000316454V602MCOSMICOvarian Cancer21720365
ENSP00000316454S59CTCGAOvarian Cancer21720365, 18772890
ENSP00000316454R203WTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
PACS1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PACS1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANPACS1_HUMANkinase -> substrateHPRD
ZAGL2_HUMANPACS1_HUMANkinase -> substrateRegPhos
PP2AA_HUMANPACS1_HUMANphosphatase -> substrateHPRD
PP2AB_HUMANPACS1_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
PACS1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019048virus-host interactionIEAbiological_process
GO:0044325ion channel bindingIPImolecular_function
GO:0000042protein targeting to GolgiIEAbiological_process
GO:0030137COPI-coated vesicleIEAcellular_component
GO:0016032viral reproductionTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0050690regulation of defense response to virus by virusTASbiological_process
GO:0072661protein targeting to plasma membraneIMPbiological_process


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