| UniProt/SwissProt ID: | NRX3B_HUMAN |
| Description: | neurexin 3 [Source:HGNC Symbol;Acc:8010] |
| Location: | chr14 q24.3 |
| Node attribute: | receptor; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S10 | IHARRsPPRRP | PhosphoSitePlus; HPRD; SysPTM | |
| S74 | ISIYRsPVSLR | PhosphoSitePlus | |
| Dephosphorylation site |
| NRX3B_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000394426 | V388I | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000394426 | H2Q | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000394426 | Q450H | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000394426 | G183S | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000394426 | F152L | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000394426 | R369Q | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| NRX3B_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NRX3B_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NLGN1_HUMAN | NRX3B_HUMAN | ligand -> receptor | HPMR |
| NLGN2_HUMAN | NRX3B_HUMAN | ligand -> receptor | HPMR |
| NXPH3_HUMAN | NRX3B_HUMAN | ligand -> receptor | HPMR |
| NXPH1_HUMAN | NRX3B_HUMAN | ligand -> receptor | HPMR |
| NLGN3_HUMAN | NRX3B_HUMAN | ligand -> receptor | HPMR |
| NRX3B_HUMAN | NLGN1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04514 | Cell adhesion molecules (CAMs) |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0001525 | angiogenesis | ISS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |