Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MYD88_HUMAN
Description:myeloid differentiation primary response 88 [Source:HGNC Symbol;Acc:7562]
Location:chr3 p22.2
Node attribute:PPI(source); PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y257LIPIKyKAMKKTIRPhosphoSitePlus
Y276ITVCDyTNPCTTIRPhosphoSitePlus

Dephosphorylation site
MYD88_HUMAN do not have dephosphorylation site.

Mutation site
MYD88_HUMAN do not have mutation site.

Differential expressed protein
MYD88_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MYD88_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TLR9_HUMANMYD88_HUMANotherKEGG
MYD88_HUMANFADD_HUMANotherKEGG
TLR4_HUMANMYD88_HUMANotherKEGG
MYD88_HUMANIRAK1_HUMANotherKEGG
TLR5_HUMANMYD88_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05143African trypanosomiasis
hsa05133Pertussis
hsa05134Legionellosis
hsa05140Leishmaniasis
hsa04620Toll-like receptor signaling pathway
hsa04064NF-kappa B signaling pathway
hsa05142Chagas disease (American trypanosomiasis)
hsa05168Herpes simplex infection
hsa05164Influenza A
hsa04210Apoptosis
hsa05162Measles
hsa05132Salmonella infection
hsa05145Toxoplasmosis
hsa05144Malaria
hsa05152Tuberculosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006954inflammatory responseIEAbiological_process
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cIEPbiological_process
GO:0032747positive regulation of interleukin-23 productionISSbiological_process
GO:0071260cellular response to mechanical stimulusIEPbiological_process
GO:0042802identical protein bindingIPImolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0034142toll-like receptor 4 signaling pathwayTASbiological_process
GO:0070555response to interleukin-1IMPbiological_process
GO:0032755positive regulation of interleukin-6 productionISSbiological_process
GO:0034130toll-like receptor 1 signaling pathwayTASbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0034134toll-like receptor 2 signaling pathwayTASbiological_process
GO:0050727regulation of inflammatory responseISSbiological_process
GO:0005829cytosolTAScellular_component
GO:0007165signal transductionNASbiological_process
GO:0008063Toll signaling pathwayTASbiological_process
GO:0045087innate immune responseTASbiological_process
GO:0032740positive regulation of interleukin-17 productionISSbiological_process
GO:0010008endosome membraneTAScellular_component
GO:00709353'-UTR-mediated mRNA stabilizationIDAbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0070976TIR domain bindingIPImolecular_function
GO:0005123death receptor bindingTASmolecular_function
GO:0002224toll-like receptor signaling pathwayTASbiological_process


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