Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MOS_HUMAN
Description:v-mos Moloney murine sarcoma viral oncogene homolog [Source:HGNC Symbol;Acc:7199]
Location:chr8 q12.1
Node attribute:kinase; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T339LLVDLtSLKAEPhosphoSitePlus
S340LVDLTsLKAELPhosphoSitePlus
Y79VYKATyRGVPVPkinasePhosphoSitePlus
S16LRSEFsPSVDAHPRD; phosphoELM
Y263PKADIySFAITPkinasePhosphoSitePlus

Dephosphorylation site
MOS_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000310722*347CCOSMICOvarian Cancer21720365
ENSP00000310722*347SCOSMICOvarian Cancer21720365
ENSP00000310722A123TGreenman2007, HPILung Cancer16140923, 17344846, 18428421
ENSP00000310722S99YBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
MOS_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MOS_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MOS_HUMANMP2K1_HUMANkinase -> substrateKEGG
MOS_HUMANTIF1A_HUMANkinase -> substrateRobert H Newman (2013)
MOS_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
MOS_HUMANMBNL3_HUMANkinase -> substrateRobert H Newman (2013)
MOS_HUMANMP2K2_HUMANkinase -> substrateKEGG
RRAS2_HUMANMOS_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04114Oocyte meiosis
hsa04914Progesterone-mediated oocyte maturation
hsa04010MAPK signaling pathway
hsa04810Regulation of actin cytoskeleton

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0040020regulation of meiosisIEAbiological_process
GO:0006468protein phosphorylationIEAbiological_process


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