Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KHDR2_HUMAN
Description:KH domain containing, RNA binding, signal transduction associated 2 [Source:HGNC Symbol;Acc:18114]
Location:chr6 q11.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y163FLVPDyNDEIRPhosphoSitePlus
S106ILGKGsMRDKAKH_1PhosphoSitePlus
Y6MEEEKyLPELMPhosphoSitePlus
T95RLQEEtGAKMSHPRD
S106ILGKGsMRDKAHPRD
S25SFVHAsRLLAEPhosphoSitePlus

Dephosphorylation site
KHDR2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000281156L28MCOSMICMelanoma21499247
ENSP00000281156L60FCOSMICMelanoma21499247
ENSP00000281156R348ICOSMICOvarian Cancer21720365
ENSP00000281156P245SCOSMICMelanoma21499247
ENSP00000281156A24VCOSMICHead and Neck Cancer21798893
ENSP00000281156H150YCOSMICMelanoma
ENSP00000281156D15ACOSMICOvarian Cancer21720365
ENSP00000281156R186CCOSMICMelanoma21499247
ENSP00000281156P19LCOSMICSkin Cancer21984974
ENSP00000281156D315HBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000281156R206LCOSMICHepatocellular Carcinoma
ENSP00000281156R224WCOSMICMelanoma21499247

Differential expressed protein
KHDR2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KHDR2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FAK2_HUMANKHDR2_HUMANkinase -> substrateRobert H Newman (2013)
JAK2_HUMANKHDR2_HUMANkinase -> substrateRobert H Newman (2013)
KSYK_HUMANKHDR2_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANKHDR2_HUMANkinase -> substrateRobert H Newman (2013)
PAK4_HUMANKHDR2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KHDR2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042169SH2 domain bindingIEAmolecular_function
GO:0008266poly(U) RNA bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0008143poly(A) RNA bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process


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