Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KC1G1_HUMAN
Description:casein kinase 1, gamma 1 [Source:HGNC Symbol;Acc:2454]
Location:chr15 q22.31
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T15ERQRTtKPMAQPhosphoSitePlus
T258GLKADtLKERYPkinase_CK1PhosphoSitePlus
T66GKNLYtNEYVAPkinase_CK1PhosphoSitePlus
T309YEYLRtLFTDLPhosphoSitePlus
Y69LYTNEyVAIKLPkinase_CK1PhosphoSitePlus
S31SRPSGsSSSSGPhosphoSitePlus
T14DERQRtTKPMAPhosphoSitePlus
S347VDSGAsAITREHPRD
Y65LGKNLyTNEYVPkinase_CK1PhosphoSitePlus
S344SVHVDsGASAIPhosphoSitePlus; HPRD
Y263TLKERyQKIGDPkinase_CK1PhosphoSitePlus
S361HRDRPsQQQPLPhosphoSitePlus; HPRD

Dephosphorylation site
KC1G1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000305777P274ACOSMICHead and Neck Cancer21798893
ENSP00000305777L249VCOSMICHead and Neck Cancer21798893

Differential expressed protein
KC1G1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KC1G1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KC1G1_HUMANZIM2_HUMANkinase -> substrateRobert H Newman (2013)
KC1G1_HUMANGCFC1_HUMANkinase -> substrateRobert H Newman (2013)
KC1G1_HUMANASAP3_HUMANkinase -> substrateRobert H Newman (2013)
KC1G1_HUMANFOXO1_HUMANkinase -> substrateHPRD
KC1G1_HUMANZN396_HUMANkinase -> substrateRobert H Newman (2013)
KC1G1_HUMANNFAC3_HUMANkinase -> substrateRobert H Newman (2013)
KC1G1_HUMANSRXN1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04340Hedgehog signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042277peptide bindingIEAmolecular_function
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0051219phosphoprotein bindingIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0001948glycoprotein bindingIEAmolecular_function
GO:0046777protein autophosphorylationIEAbiological_process
GO:0000287magnesium ion bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component


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