| UniProt/SwissProt ID: | KC1G1_HUMAN |
| Description: | casein kinase 1, gamma 1 [Source:HGNC Symbol;Acc:2454] |
| Location: | chr15 q22.31 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T15 | ERQRTtKPMAQ | PhosphoSitePlus | |
| T258 | GLKADtLKERY | Pkinase_CK1 | PhosphoSitePlus |
| T66 | GKNLYtNEYVA | Pkinase_CK1 | PhosphoSitePlus |
| T309 | YEYLRtLFTDL | PhosphoSitePlus | |
| Y69 | LYTNEyVAIKL | Pkinase_CK1 | PhosphoSitePlus |
| S31 | SRPSGsSSSSG | PhosphoSitePlus | |
| T14 | DERQRtTKPMA | PhosphoSitePlus | |
| S347 | VDSGAsAITRE | HPRD | |
| Y65 | LGKNLyTNEYV | Pkinase_CK1 | PhosphoSitePlus |
| S344 | SVHVDsGASAI | PhosphoSitePlus; HPRD | |
| Y263 | TLKERyQKIGD | Pkinase_CK1 | PhosphoSitePlus |
| S361 | HRDRPsQQQPL | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| KC1G1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000305777 | P274A | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000305777 | L249V | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| KC1G1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KC1G1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KC1G1_HUMAN | ZIM2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KC1G1_HUMAN | GCFC1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KC1G1_HUMAN | ASAP3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KC1G1_HUMAN | FOXO1_HUMAN | kinase -> substrate | HPRD |
| KC1G1_HUMAN | ZN396_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KC1G1_HUMAN | NFAC3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KC1G1_HUMAN | SRXN1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04340 | Hedgehog signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0042277 | peptide binding | IEA | molecular_function |
| GO:0016055 | Wnt receptor signaling pathway | IEA | biological_process |
| GO:0051219 | phosphoprotein binding | IEA | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0001948 | glycoprotein binding | IEA | molecular_function |
| GO:0046777 | protein autophosphorylation | IEA | biological_process |
| GO:0000287 | magnesium ion binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |