| UniProt/SwissProt ID: | ZIM2_HUMAN |
| Description: | zinc finger, imprinted 2 [Source:HGNC Symbol;Acc:12875] |
| Location: | chr19 q13.43 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T13 | NNSDVtSDDDM | PhosphoSitePlus | |
| S14 | NSDVTsDDDMT | PhosphoSitePlus | |
| Y411 | HSQEDyFECFQ | PhosphoSitePlus | |
| S10 | EDDNNsDVTSD | PhosphoSitePlus | |
| S63 | TRNPRsRMPPR | PhosphoSitePlus | |
| S71 | PPRDLsLPVVA | PhosphoSitePlus | |
| Y2 | ____MyQPEDD | PhosphoSitePlus | |
| T19 | SDDDMtRNRRE | PhosphoSitePlus | |
| Dephosphorylation site |
| ZIM2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000221722 | N328K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000221722 | R68W | COSMIC | Ovarian Cancer | 21720365 | ENSP00000375589 | S139F | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000375589 | E189X | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000221722 | R505* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000221722 | S139F | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000221722 | F178L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000221722 | P115L | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000375589 | P115L | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
| Differential expressed protein |
| ZIM2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZIM2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KC1G1_HUMAN | ZIM2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZIM2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | NAS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0008270 | zinc ion binding | NAS | molecular_function |
| GO:0003677 | DNA binding | NAS | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005575 | cellular_component | ND | cellular_component |