Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IL5_HUMAN
Description:interleukin 5 (colony-stimulating factor, eosinophil) [Source:HGNC Symbol;Acc:6016]
Location:chr5 q31.1
Node attribute:gene

Phosphorylation site
IL5_HUMAN do not have phosphorylation site.

Dephosphorylation site
IL5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000231454I131KCOSMICHead and Neck Cancer21798893

Differential expressed protein
IL5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IL5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FOSL2_HUMANIL5_HUMANTF -> target geneTRANSFAC
PO2F2_HUMANIL5_HUMANTF -> target geneTRANSFAC
PO2F1_HUMANIL5_HUMANTF -> target geneTRANSFAC
JUND_HUMANIL5_HUMANTF -> target geneTRANSFAC
GATA2_HUMANIL5_HUMANTF -> target geneTRANSFAC
JUN_HUMANIL5_HUMANTF -> target geneTRANSFAC
GATA4_HUMANIL5_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
IL5_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0050731positive regulation of peptidyl-tyrosine phosphoryISSbiological_process
GO:0005137interleukin-5 receptor bindingIEAmolecular_function
GO:0051091positive regulation of sequence-specific DNA bindiIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0051024positive regulation of immunoglobulin secretionIEAbiological_process
GO:0005576extracellular regionIDAcellular_component
GO:0030890positive regulation of B cell proliferationIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0006955immune responseIEAbiological_process
GO:0046427positive regulation of JAK-STAT cascadeIEAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0019221cytokine-mediated signaling pathwayIEAbiological_process
GO:0005125cytokine activityIEAmolecular_function
GO:0006954inflammatory responseIEAbiological_process
GO:0005615extracellular spaceTAScellular_component
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0071803positive regulation of podosome assemblyIDAbiological_process
GO:0045645positive regulation of eosinophil differentiationIEAbiological_process


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