Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GTR4_HUMAN
Description:solute carrier family 2 (facilitated glucose transporter), member 4 [Source:HGNC Symbol;Acc:11009]
Location:chr17 p13.1
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y502STELEyLGPDEPhosphoSitePlus
S274RERPLsLLQLLSugar_trPhosphoSitePlus
T486AAFHRtPSLLEHPRD; phosphoELM
S281LQLLGsRTHRQSugar_trPhosphoSitePlus
Y56VIEQSyNETWLSugar_trPhosphoSitePlus
S274RERPLsLLQLLphosphoELM

Dephosphorylation site
GTR4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000320935G207RCOSMICOvarian Cancer21720365
ENSP00000320935Y308HCOSMICHead and Neck Cancer21798893

Differential expressed protein
GTR4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GTR4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CIP4_HUMANGTR4_HUMANotherKEGG
KPCI_HUMANGTR4_HUMANotherKEGG
EXOC7_HUMANGTR4_HUMANotherKEGG
AKT3_HUMANGTR4_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04930Type II diabetes mellitus
hsa04920Adipocytokine signaling pathway
hsa04910Insulin signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005355glucose transmembrane transporter activityTASmolecular_function
GO:0055056D-glucose transmembrane transporter activityIEAmolecular_function
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0048471perinuclear region of cytoplasmIDAcellular_component
GO:0032869cellular response to insulin stimulusIDAbiological_process
GO:0012505endomembrane systemISScellular_component
GO:0005905coated pitIEAcellular_component
GO:0045471response to ethanolIEAbiological_process
GO:0010021amylopectin biosynthetic processIEAbiological_process
GO:0005355glucose transmembrane transporter activityIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0055085transmembrane transportTASbiological_process
GO:0016020membraneTAScellular_component
GO:0032593insulin-responsive compartmentIEAcellular_component
GO:0005886plasma membraneIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0015758glucose transportIEAbiological_process
GO:0022857transmembrane transporter activityIEAmolecular_function
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0030136clathrin-coated vesicleIDAcellular_component
GO:0042383sarcolemmaIEAcellular_component
GO:0071470cellular response to osmotic stressIEAbiological_process
GO:0050873brown fat cell differentiationIEAbiological_process
GO:0022891substrate-specific transmembrane transporter activIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0070062extracellular vesicular exosomeIEAcellular_component
GO:0008645hexose transportTASbiological_process
GO:0030140trans-Golgi network transport vesicleIEAcellular_component
GO:0042593glucose homeostasisIDAbiological_process
GO:0015758glucose transportTASbiological_process
GO:0005768endosomeIEAcellular_component
GO:0032593insulin-responsive compartmentISScellular_component
GO:0012506vesicle membraneIDAcellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005975carbohydrate metabolic processTASbiological_process
GO:0046323glucose importNASbiological_process
GO:0009897external side of plasma membraneIDAcellular_component
GO:0005887integral to plasma membraneIEAcellular_component
GO:0043231intracellular membrane-bounded organelleIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0005771multivesicular bodyIEAcellular_component


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