| UniProt/SwissProt ID: | EXOC7_HUMAN |
| Description: | exocyst complex component 7 [Source:HGNC Symbol;Acc:23214] |
| Location: | chr17 q25.1 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S385 | PGLITsMETIG | HPRD | |
| Y90 | DHVISyYHVAS | COG5; Poty_PP | PhosphoSitePlus |
| T384 | LPGLItSMETI | HPRD | |
| Y249 | SSGVPySPAIP | PhosphoSitePlus | |
| T271 | VKRPGtIRKAQ | PhosphoSitePlus | |
| S250 | SGVPYsPAIPN | PhosphoSitePlus; HPRD; phosphoELM | |
| S224 | YYQIRsSQLDR | PhosphoSitePlus | |
| S225 | YQIRSsQLDRS | PhosphoSitePlus | |
| S130 | YFQDNsPDSPE | PhosphoSitePlus | |
| Y125 | QKAVEyFQDNS | PhosphoSitePlus | |
| Dephosphorylation site |
| EXOC7_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000384368 | N477K | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000384368 | H285R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000334100 | H285R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000349767 | N454K | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000334100 | N505K | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000404322 | N446K | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000349767 | H285R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000349767 | *685S | COSMIC | Breast Cancer | 16959974 | ENSP00000333806 | N423K | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| EXOC7_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| EXOC7_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| EXOC7_HUMAN | GTR4_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04910 | Insulin signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005829 | cytosol | IEA | cellular_component |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0006887 | exocytosis | IEA | biological_process |
| GO:0005815 | microtubule organizing center | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0032584 | growth cone membrane | IEA | cellular_component |
| GO:0034451 | centriolar satellite | IDA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0000145 | exocyst | IEA | cellular_component |