Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GLUC_HUMAN
Description:glucagon [Source:HGNC Symbol;Acc:4191]
Location:chr2 q24.2
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T26RSLQDtEEKSRPhosphoSitePlus
S34KSRSFsASQADPhosphoSitePlus
Y62TFTSDySKYLDHormone_2PhosphoSitePlus
S42QADPLsDPDQMPhosphoSitePlus
S68SKYLDsRRAQDHormone_2PhosphoSitePlus
S32EEKSRsFSASQPhosphoSitePlus
S36RSFSAsQADPLPhosphoSitePlus

Dephosphorylation site
GLUC_HUMAN do not have dephosphorylation site.

Mutation site
GLUC_HUMAN do not have mutation site.

Differential expressed protein
GLUC_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GLUC_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GLUC_HUMANGLP2R_HUMANligand -> receptorHPMR
GLUC_HUMANGLR_HUMANligand -> receptorHPMR
GLUC_HUMANGLP1R_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
GLUC_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005102receptor bindingTASmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0006112energy reserve metabolic processTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0008283cell proliferationTASbiological_process
GO:0010800positive regulation of peptidyl-threonine phosphorIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0030141secretory granuleTAScellular_component
GO:0050796regulation of insulin secretionIEAbiological_process
GO:0033138positive regulation of peptidyl-serine phosphorylaIEAbiological_process
GO:0010737protein kinase A signaling cascadeIEAbiological_process
GO:0007631feeding behaviorTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0032092positive regulation of protein bindingIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0045860positive regulation of protein kinase activityIEAbiological_process
GO:0050796regulation of insulin secretionTASbiological_process
GO:0005788endoplasmic reticulum lumenTAScellular_component
GO:0071377cellular response to glucagon stimulusTASbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0030819positive regulation of cAMP biosynthetic processIEAbiological_process
GO:0070374positive regulation of ERK1 and ERK2 cascadeIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0035774positive regulation of insulin secretion involved IEAbiological_process
GO:0090280positive regulation of calcium ion importIEAbiological_process
GO:0007165signal transductionTASbiological_process


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