Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GBRR1_HUMAN
Description:gamma-aminobutyric acid (GABA) A receptor, rho 1 [Source:HGNC Symbol;Acc:4090]
Location:chr6 q15
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S166VHSKRsFIHDTNeur_chan_LBDPhosphoSitePlus
T394LPPPRtAMLDGMAPK1HPRD
S431QLTLAsERSSPPRKCAHPRD
Y219LEIESyAYTEDNeur_chan_LBDPhosphoSitePlus
S435ASERSsPQRKSMAPK1HPRD
S444KSQRSsYVSMRPRKG1HPRD
Y221IESYAyTEDDLNeur_chan_LBDPhosphoSitePlus
Y229DDLMLyWKKGNNeur_chan_LBDPhosphoSitePlus
S440SPQRKsQRSSYMAPK1HPRD
S447RSSYVsMRIDTPRKCAHPRD
S402LDGNYsDGEVNCSNK2A1HPRD
S443RKSQRsSYVSMPRKCAHPRD
T171SFIHDtTTDNVNeur_chan_LBDPhosphoSitePlus
S440SPQRKsQRSSYPRKCAHPRD
S444KSQRSsYVSMRPRKACAHPRD
S443RKSQRsSYVSMHPRD
T172FIHDTtTDNVMNeur_chan_LBDPhosphoSitePlus
S444KSQRSsYVSMRPRKCAHPRD

Dephosphorylation site
GBRR1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000412673D66EBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
GBRR1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GBRR1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANGBRR1_HUMANkinase -> substrateHPRD
KGP1_HUMANGBRR1_HUMANkinase -> substrateHPRD
CSK21_HUMANGBRR1_HUMANkinase -> substrateHPRD
MK01_HUMANGBRR1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04723Retrograde endocannabinoid signaling
hsa04727GABAergic synapse
hsa05033Nicotine addiction
hsa04080Neuroactive ligand-receptor interaction
hsa05032Morphine addiction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0034707chloride channel complexIEAcellular_component
GO:0045211postsynaptic membraneIEAcellular_component
GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0007268synaptic transmissionTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0055085transmembrane transportTASbiological_process
GO:0006810transportTASbiological_process
GO:0034220ion transmembrane transportTASbiological_process
GO:0030054cell junctionIEAcellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0007214gamma-aminobutyric acid signaling pathwayTASbiological_process
GO:0005254chloride channel activityIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0005230extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0006811ion transportIEAbiological_process


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