Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DRD5_HUMAN
Description:dopamine receptor D5 [Source:HGNC Symbol;Acc:3026]
Location:chr4 p16.1
Node attribute:receptor; GPCR

Phosphorylation site
DRD5_HUMAN do not have phosphorylation site.

Dephosphorylation site
DRD5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000306129G190WCOSMICMelanoma21499247

Differential expressed protein
DRD5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DRD5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TY3H_HUMANDRD5_HUMANligand -> receptorHPMR
DRD5_HUMANGNA13_HUMANGPCR -> GproteingpDB
DRD5_HUMANGNAS2_HUMANGPCR -> GproteingpDB
DRD5_HUMANGNAS1_HUMANGPCR -> GproteingpDB
DRD5_HUMANGNA12_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04020Calcium signaling pathway
hsa04080Neuroactive ligand-receptor interaction
hsa04728Dopaminergic synapse

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060158phospholipase C-activating dopamine receptor signaTASbiological_process
GO:0046960sensitizationIEAbiological_process
GO:0008306associative learningIEAbiological_process
GO:0001588dopamine neurotransmitter receptor activity, couplIEAmolecular_function
GO:0033861negative regulation of NAD(P)H oxidase activityIDAbiological_process
GO:0001588dopamine neurotransmitter receptor activity, couplTASmolecular_function
GO:0001992regulation of systemic arterial blood pressure by IEAbiological_process
GO:0071870cellular response to catecholamine stimulusIDAbiological_process
GO:0006874cellular calcium ion homeostasisTASbiological_process
GO:0007191adenylate cyclase-activating dopamine receptor sigIDAbiological_process
GO:0007617mating behaviorIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0045924regulation of female receptivityIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0007189adenylate cyclase-activating G-protein coupled recIDAbiological_process
GO:0001975response to amphetamineIEAbiological_process
GO:0031526brush border membraneIEAcellular_component
GO:0045776negative regulation of blood pressureIEAbiological_process
GO:0001994norepinephrine-epinephrine vasoconstriction involvIEAbiological_process
GO:0004952dopamine neurotransmitter receptor activityIDAmolecular_function
GO:0060292long term synaptic depressionIEAbiological_process
GO:0007190activation of adenylate cyclase activityTASbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007268synaptic transmissionNASbiological_process
GO:0035240dopamine bindingIDAmolecular_function
GO:0005887integral to plasma membraneNAScellular_component
GO:0042220response to cocaineIEAbiological_process
GO:0072593reactive oxygen species metabolic processIDAbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0019226transmission of nerve impulseIEAbiological_process
GO:0001963synaptic transmission, dopaminergicNASbiological_process
GO:0042060wound healingIEAbiological_process
GO:0045762positive regulation of adenylate cyclase activityIDAbiological_process


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