| UniProt/SwissProt ID: | CXL11_HUMAN |
| Description: | chemokine (C-X-C motif) ligand 11 [Source:HGNC Symbol;Acc:10638] |
| Location: | chr4 q21.1 |
| Node attribute: | PPI(source); ligand; gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y52 | KASIMyPSNNC | IL8 | PhosphoSitePlus |
| S49 | DIEKAsIMYPS | IL8 | PhosphoSitePlus |
| Dephosphorylation site |
| CXL11_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CXL11_HUMAN do not have mutation site. |
| Differential expressed protein |
| CXL11_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CXL11_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CXL11_HUMAN | CXCR3_HUMAN | ligand -> receptor | HPMR |
| CXL11_HUMAN | CXCR3_HUMAN | other | KEGG |
| CXL11_HUMAN | CXCR7_HUMAN | other | KEGG |
| IRF3_HUMAN | CXL11_HUMAN | TF -> target gene | KEGG |
| STAT1_HUMAN | CXL11_HUMAN | TF -> target gene | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04062 | Chemokine signaling pathway |
| hsa04620 | Toll-like receptor signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006955 | immune response | IEA | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0006935 | chemotaxis | IEA | biological_process |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0006954 | inflammatory response | IEA | biological_process |
| GO:0008009 | chemokine activity | IEA | molecular_function |