Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CEAM1_HUMAN
Description:carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) [Source:HGNC Symbol;Acc:1814]
Location:chr19 q13.2
Node attribute:substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y493MNEVTySTLNFSRCHPRD; RegPhos
Y493MNEVTySTLNFDUF2668PhosphoSitePlus
Y520ATEIIySEVKKPhosphoSitePlus; RegPhos
S461KTGRAsDQRDLDUF2668; Form-deh_transPhosphoSitePlus
T492KMNEVtYSTLNDUF2668PhosphoSitePlus
S521TEIIYsEVKKQPhosphoSitePlus
T457LHFGKtGRASDDUF2668; Form-deh_transPhosphoSitePlus
Y493MNEVTySTLNFphosphoELM; RegPhos
Y520ATEIIySEVKphosphoELM
S508PTQPTsASPSLMLK2RegPhos
S508PTQPTsASPSLDUF2668PhosphoSitePlus
S508PTQPTsASPSLphosphoELM; RegPhos
Y520ATEIIySEVKKSRCRegPhos
S508PTQPTsASPSLMAP3K10HPRD
S494NEVTYsTLNFEDUF2668PhosphoSitePlus
Y520ATEIIySEVKSRCHPRD

Dephosphorylation site
CEAM1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000161559C308GCOSMICOvarian Cancer21720365

Differential expressed protein
CEAM1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CEAM1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
M3K10_HUMANCEAM1_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANCEAM1_HUMANkinase -> substrateRegPhos
SRC_HUMANCEAM1_HUMANkinase -> substrateRegPhos
HNF4A_HUMANCEAM1_HUMANTF -> target geneTRANSFAC
USF1_HUMANCEAM1_HUMANTF -> target geneTRANSFAC
AP2A_HUMANCEAM1_HUMANTF -> target geneTRANSFAC
HNF4G_HUMANCEAM1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
CEAM1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001525angiogenesisNASbiological_process
GO:0016021integral to membraneIDAcellular_component
GO:0003674molecular_functionNDmolecular_function
GO:0005887integral to plasma membraneNAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0016477cell migrationNASbiological_process
GO:0016020membraneTAScellular_component
GO:0007229integrin-mediated signaling pathwayNASbiological_process
GO:0007156homophilic cell adhesionNASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0005576extracellular regionIEAcellular_component


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