| UniProt/SwissProt ID: | CEAM1_HUMAN |
| Description: | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) [Source:HGNC Symbol;Acc:1814] |
| Location: | chr19 q13.2 |
| Node attribute: | substrate; gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y493 | MNEVTySTLNF | SRC | HPRD; RegPhos |
| Y493 | MNEVTySTLNF | DUF2668 | PhosphoSitePlus |
| Y520 | ATEIIySEVKK | PhosphoSitePlus; RegPhos | |
| S461 | KTGRAsDQRDL | DUF2668; Form-deh_trans | PhosphoSitePlus |
| T492 | KMNEVtYSTLN | DUF2668 | PhosphoSitePlus |
| S521 | TEIIYsEVKKQ | PhosphoSitePlus | |
| T457 | LHFGKtGRASD | DUF2668; Form-deh_trans | PhosphoSitePlus |
| Y493 | MNEVTySTLNF | phosphoELM; RegPhos | |
| Y520 | ATEIIySEVK | phosphoELM | |
| S508 | PTQPTsASPSL | MLK2 | RegPhos |
| S508 | PTQPTsASPSL | DUF2668 | PhosphoSitePlus |
| S508 | PTQPTsASPSL | phosphoELM; RegPhos | |
| Y520 | ATEIIySEVKK | SRC | RegPhos |
| S508 | PTQPTsASPSL | MAP3K10 | HPRD |
| S494 | NEVTYsTLNFE | DUF2668 | PhosphoSitePlus |
| Y520 | ATEIIySEVK | SRC | HPRD |
| Dephosphorylation site |
| CEAM1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000161559 | C308G | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| CEAM1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CEAM1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| M3K10_HUMAN | CEAM1_HUMAN | kinase -> substrate | HPRD; RegPhos |
| ZAGL2_HUMAN | CEAM1_HUMAN | kinase -> substrate | RegPhos |
| SRC_HUMAN | CEAM1_HUMAN | kinase -> substrate | RegPhos |
| HNF4A_HUMAN | CEAM1_HUMAN | TF -> target gene | TRANSFAC |
| USF1_HUMAN | CEAM1_HUMAN | TF -> target gene | TRANSFAC |
| AP2A_HUMAN | CEAM1_HUMAN | TF -> target gene | TRANSFAC |
| HNF4G_HUMAN | CEAM1_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| CEAM1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0001525 | angiogenesis | NAS | biological_process |
| GO:0016021 | integral to membrane | IDA | cellular_component |
| GO:0003674 | molecular_function | ND | molecular_function |
| GO:0005887 | integral to plasma membrane | NAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016477 | cell migration | NAS | biological_process |
| GO:0016020 | membrane | TAS | cellular_component |
| GO:0007229 | integrin-mediated signaling pathway | NAS | biological_process |
| GO:0007156 | homophilic cell adhesion | NAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005576 | extracellular region | IEA | cellular_component |