| UniProt/SwissProt ID: | CDK18_HUMAN |
| Description: | cyclin-dependent kinase 18 [Source:HGNC Symbol;Acc:8751] |
| Location: | chr1 q32.1 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S14 | FKRRFsLSVPR | HPRD | |
| S14 | RRFSLsVPRTE | PhosphoSitePlus | |
| S62 | ECSTFsPTDSG | HPRD | |
| S98 | VSKRLsLPMDI | HPRD | |
| Y185 | LGEGTyATVFK | HPRD | |
| T187 | EGTYAtVFKGR | HPRD | |
| S502 | KNRRQs | HPRD | |
| S12 | FKRRFsLSVPR | PhosphoSitePlus; phosphoELM | |
| T155 | EGTYAtVFKGR | Pkinase | PhosphoSitePlus |
| S96 | VSKRLsLPMDI | PhosphoSitePlus | |
| S164 | RRASLsDIGFG | HPRD | |
| S115 | KLQMEsPDLPK | PhosphoSitePlus | |
| T152 | KLGEGtYATVF | Pkinase | PhosphoSitePlus |
| T157 | EGTYAtVFKGR | HPRD | |
| S134 | RRASLsDIGFG | HPRD | |
| S72 | EPGQLsPGVQF | PhosphoSitePlus | |
| T141 | FGKLEtYVKLD | PhosphoSitePlus | |
| Y155 | LGEGTyATVFK | HPRD | |
| S470 | KNRRQsIF___ | PhosphoSitePlus | |
| S128 | VSKRLsLPMDI | HPRD | |
| Y153 | LGEGTyATVFK | Pkinase | PhosphoSitePlus |
| S130 | MSRRAsLSDIG | PhosphoSitePlus; phosphoELM | |
| S87 | NQRRFsMEDVS | PhosphoSitePlus; phosphoELM | |
| S117 | KLQMEsPDLPK | HPRD | |
| S147 | KLQMEsPDLPK | HPRD | |
| S472 | KNRRQs | HPRD | |
| S89 | NQRRFsMEDVS | HPRD | |
| S132 | MSRRAsLSDIG | HPRD | |
| S74 | EPGQLsPGVQF | HPRD | |
| S132 | RRASLsDIGFG | PhosphoSitePlus; phosphoELM | |
| S162 | MSRRAsLSDIG | HPRD | |
| Dephosphorylation site |
| CDK18_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CDK18_HUMAN do not have mutation site. |
| Differential expressed protein |
| CDK18_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CDK18_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK18_HUMAN | GRK5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK18_HUMAN | CIP4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK18_HUMAN | SMAD3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK18_HUMAN | ZYX_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| CDK18_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0004871 | signal transducer activity | NAS | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | NAS | biological_process |
| GO:0004674 | protein serine/threonine kinase activity | NAS | molecular_function |
| GO:0007165 | signal transduction | NAS | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0004693 | cyclin-dependent protein kinase activity | IEA | molecular_function |