Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CAC1A_HUMAN
Description:calcium channel, voltage-dependent, P/Q type, alpha 1A subunit [Source:HGNC Symbol;Acc:1388]
Location:chr19 p13.2
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y12EMPARyGGGGSPhosphoSitePlus
Y1014GAPATyEGDARPhosphoSitePlus
T2274SPAPStSGTSTPhosphoSitePlus
T2279TSGTStPRRGRPhosphoSitePlus
S2265RQGSSsVSGSPPhosphoSitePlus
Y1424GKYLLyEKNEVIon_transPhosphoSitePlus
S910HAREGsLEQPGPhosphoSitePlus
Y1421DCRGKyLLYEKIon_transPhosphoSitePlus
S2263AHRQGsSSVSGPhosphoSitePlus
S2267GSSSVsGSPAPPhosphoSitePlus
S947ESRSGsPRTGAPhosphoSitePlus

Dephosphorylation site
CAC1A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000317661R369WBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
CAC1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CAC1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBG10_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG8_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG1_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBB2_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBB3_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG13_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG2_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG3_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG5_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GNAO_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBB5_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG11_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBB1_HUMANCAC1A_HUMANGprotein -> effectorgpDB
GBG12_HUMANCAC1A_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04727GABAergic synapse
hsa04723Retrograde endocannabinoid signaling
hsa05033Nicotine addiction
hsa05032Morphine addiction
hsa04725Cholinergic synapse
hsa04730Long-term depression
hsa04721Synaptic vesicle cycle
hsa04726Serotonergic synapse
hsa04742Taste transduction
hsa04724Glutamatergic synapse
hsa04020Calcium signaling pathway
hsa04010MAPK signaling pathway
hsa04728Dopaminergic synapse
hsa04930Type II diabetes mellitus

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044281small molecule metabolic processTASbiological_process
GO:0055085transmembrane transportIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0019905syntaxin bindingIDAmolecular_function
GO:0005891voltage-gated calcium channel complexIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0050796regulation of insulin secretionTASbiological_process
GO:0008219cell deathIDAbiological_process
GO:0007204elevation of cytosolic calcium ion concentrationISSbiological_process
GO:0005216ion channel activityIEAmolecular_function
GO:0016021integral to membraneTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0051899membrane depolarizationTASbiological_process
GO:0005245voltage-gated calcium channel activityISSmolecular_function
GO:0007268synaptic transmissionTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006811ion transportIEAbiological_process
GO:0042995cell projectionIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0046872metal ion bindingIEAmolecular_function
GO:0006112energy reserve metabolic processTASbiological_process