Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ARPC5_HUMAN
Description:actin related protein 2/3 complex, subunit 5, 16kDa [Source:HGNC Symbol;Acc:708]
Location:chr1 q25.3
Node attribute:substrate; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S140AGGVGsIVRVLP16-ArcPhosphoSitePlus
T146IVRVLtARKTVP16-ArcPhosphoSitePlus
S77KDRAGsIVLKVMAPKAPK2HPRD
Y19VDVDEyDENKFP16-ArcPhosphoSitePlus
S77KDRAGsIVLKVP16-ArcPhosphoSitePlus

Dephosphorylation site
ARPC5_HUMAN do not have dephosphorylation site.

Mutation site
ARPC5_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000352918Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
ARPC5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MAPK2_HUMANARPC5_HUMANkinase -> substrateHPRD
WASP_HUMANARPC5_HUMANotherKEGG
WASF2_HUMANARPC5_HUMANotherKEGG
SL9A1_HUMANARPC5_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05100Bacterial invasion of epithelial cells
hsa04810Regulation of actin cytoskeleton
hsa05132Salmonella infection
hsa04666Fc gamma R-mediated phagocytosis
hsa05131Shigellosis
hsa05130Pathogenic Escherichia coli infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030036actin cytoskeleton organizationTASbiological_process
GO:0005200structural constituent of cytoskeletonTASmolecular_function
GO:0015629actin cytoskeletonTAScellular_component
GO:0006928cellular component movementTASbiological_process
GO:0003779actin bindingIEAmolecular_function
GO:0005885Arp2/3 protein complexTAScellular_component
GO:0030027lamellipodiumIEAcellular_component
GO:0005856cytoskeletonIEAcellular_component
GO:0030833regulation of actin filament polymerizationIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function


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