Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ADCY7_HUMAN
Description:adenylate cyclase 7 [Source:HGNC Symbol;Acc:238]
Location:chr16 q12.1
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T809VLFYItLLTLSTMPhosphoSitePlus
S814TLLTLsRQIDYTMPhosphoSitePlus
T812YITLLtLSRQITMPhosphoSitePlus
T155VGAVStASHLLTMPhosphoSitePlus
Y807YLVLFyITLLTTMPhosphoSitePlus
T365QVREAtGVDINGuanylate_cycPhosphoSitePlus
S154AVGAVsTASHLTMPhosphoSitePlus
S157AVSTAsHLLVLTMPhosphoSitePlus

Dephosphorylation site
ADCY7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000378187E431KCOSMICMelanoma21499247

Differential expressed protein
ADCY7_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ADCY7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBB5_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG10_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG3_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBB2_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG8_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBB3_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG2_HUMANADCY7_HUMANGprotein -> effectorgpDB
GNAS2_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBB1_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG5_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG12_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG1_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG11_HUMANADCY7_HUMANGprotein -> effectorgpDB
GNAS1_HUMANADCY7_HUMANGprotein -> effectorgpDB
GBG13_HUMANADCY7_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05032Morphine addiction
hsa05166HTLV-I infection
hsa04020Calcium signaling pathway
hsa04062Chemokine signaling pathway
hsa04914Progesterone-mediated oocyte maturation
hsa04970Salivary secretion
hsa04725Cholinergic synapse
hsa04270Vascular smooth muscle contraction
hsa05414Dilated cardiomyopathy
hsa04912GnRH signaling pathway
hsa04976Bile secretion
hsa04540Gap junction
hsa04971Gastric acid secretion
hsa04724Glutamatergic synapse
hsa04723Retrograde endocannabinoid signaling
hsa04916Melanogenesis
hsa04727GABAergic synapse
hsa04972Pancreatic secretion
hsa04114Oocyte meiosis
hsa00230Purine metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0035556intracellular signal transductionIEAbiological_process
GO:0004016adenylate cyclase activityIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0071361cellular response to ethanolIDAbiological_process
GO:0071377cellular response to glucagon stimulusTASbiological_process
GO:0007193adenylate cyclase-inhibiting G-protein coupled recTASbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0055085transmembrane transportTASbiological_process
GO:0030819positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0006112energy reserve metabolic processTASbiological_process
GO:0007202activation of phospholipase C activityTASbiological_process
GO:0016021integral to membraneIDAcellular_component
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0007173epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0009190cyclic nucleotide biosynthetic processIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0034199activation of protein kinase A activityTASbiological_process
GO:0006833water transportTASbiological_process
GO:0005886plasma membraneISScellular_component
GO:0008543fibroblast growth factor receptor signaling pathwaTASbiological_process
GO:0007268synaptic transmissionTASbiological_process
GO:0016849phosphorus-oxygen lyase activityIEAmolecular_function
GO:0007165signal transductionTASbiological_process


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