Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ADA2C_HUMAN
Description:adrenoceptor alpha 2C [Source:HGNC Symbol;Acc:283]
Location:chr4 p16.3
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S338LTASRsPGPGG7tm_1PhosphoSitePlus

Dephosphorylation site
ADA2C_HUMAN do not have dephosphorylation site.

Mutation site
ADA2C_HUMAN do not have mutation site.

Differential expressed protein
ADA2C_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ADA2C_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DOPO_HUMANADA2C_HUMANligand -> receptorHPMR
ADA2C_HUMANGNAO_HUMANGPCR -> GproteingpDB
ADA2C_HUMANGNAI2_HUMANGPCR -> GproteingpDB
ADA2C_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADA2C_HUMANGNAI1_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0031694alpha-2A adrenergic receptor bindingIPImolecular_function
GO:0050796regulation of insulin secretionTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0071883activation of MAPK activity by adrenergic receptorIDAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0005887integral to plasma membraneIDAcellular_component
GO:0032811negative regulation of epinephrine secretionNASbiological_process
GO:0035625epidermal growth factor-activated receptor transacIDAbiological_process
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0043679axon terminusIEAcellular_component
GO:0030424axonIEAcellular_component
GO:0004938alpha2-adrenergic receptor activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0007267cell-cell signalingTASbiological_process
GO:0051379epinephrine bindingIDAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0051930regulation of sensory perception of painIEAbiological_process
GO:0042803protein homodimerization activityIDAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0045666positive regulation of neuron differentiationIDAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0070473negative regulation of uterine smooth muscle contrIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0032148activation of protein kinase B activityIDAbiological_process
GO:0005768endosomeTAScellular_component
GO:0045907positive regulation of vasoconstrictionIEAbiological_process
GO:0030168platelet activationTASbiological_process
GO:0006112energy reserve metabolic processTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0004938alpha2-adrenergic receptor activityIDAmolecular_function
GO:0007565female pregnancyIEAbiological_process
GO:0010700negative regulation of norepinephrine secretionNASbiological_process