Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:2A5A_HUMAN
Description:protein phosphatase 2, regulatory subunit B', alpha [Source:HGNC Symbol;Acc:9309]
Location:chr1 q32.3
Node attribute:substrate; phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S46SSQFRsQGSQAPhosphoSitePlus
S28GFTRKsVRKAQEIF2AK2HPRD
Y474KQNSAyNMHSIPhosphoSitePlus
S41KRSQGsSQFRSPhosphoSitePlus; HPRD; phosphoELM
S28GFTRKsVRKAQPhosphoSitePlus; phosphoELM; RegPhos
S28GFTRKsVRKAQPKRRegPhos
S42RSQGSsQFRSQPhosphoSitePlus; HPRD; phosphoELM
S472LEKQNsAYNMHPhosphoSitePlus; HPRD
S484ILSNTsAE___PhosphoSitePlus
S38QRQKRsQGSSQPhosphoSitePlus
S49FRSQGsQAELHPhosphoSitePlus

Dephosphorylation site
2A5A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000261461Q324KCOSMICOvarian Cancer21720365
ENSP00000446035Q324KCOSMICOvarian Cancer21720365
ENSP00000442866Q267KTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
2A5A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
2A5A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMAN2A5A_HUMANkinase -> substrateRegPhos
CDK4_HUMAN2A5A_HUMANkinase -> substrateRobert H Newman (2013)
E2AK2_HUMAN2A5A_HUMANkinase -> substrateHPRD; RegPhos
2A5A_HUMANTAU_HUMANphosphatase -> substrateHPRD
2A5A_HUMANNOS3_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03015mRNA surveillance pathway
hsa04310Wnt signaling pathway
hsa04728Dopaminergic synapse
hsa04114Oocyte meiosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019900kinase bindingIPImolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0016020membraneIDAcellular_component
GO:0005488bindingIEAmolecular_function
GO:0031430M bandISScellular_component
GO:0000775chromosome, centromeric regionIEAcellular_component
GO:0035307positive regulation of protein dephosphorylationIMPbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0000159protein phosphatase type 2A complexIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0030018Z discIEAcellular_component
GO:0090005negative regulation of establishment of protein loIMPbiological_process
GO:0008601protein phosphatase type 2A regulator activityIEAmolecular_function
GO:0090219negative regulation of lipid kinase activityIMPbiological_process
GO:0005634nucleusIEAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23