Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZCHC8_HUMAN
Description:zinc finger, CCHC domain containing 8 [Source:HGNC Symbol;Acc:25265]
Location:chr12 q24.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T88ILVNDtKLDGPHPRD
S658ATKIHsPIPDMPhosphoSitePlus; HPRD; phosphoELM
S373PGFNIsTPRGIPhosphoSitePlus
S498PPLTPsDSPQTPhosphoSitePlus; HPRD
T492PLPKGtPPLTPPhosphoSitePlus; HPRD; phosphoELM
Y258EKRKEyMDACGPhosphoSitePlus
S500LTPSDsPQTRTPhosphoSitePlus; HPRD; phosphoELM
Y336SGLALyDGKDGPhosphoSitePlus
S427HSSPGsPKKQKPhosphoSitePlus
S601ASSPDsEVTSLPhosphoSitePlus; HPRD
T88ILVNDtKLDGPHerpes_BLRF2PhosphoSitePlus
S640ISNGGsQKLFPPhosphoSitePlus; HPRD; phosphoELM
S598AGHASsPDSEVPhosphoSitePlus; HPRD; phosphoELM
T652DTSPStATKIHPhosphoSitePlus
S636PNCDIsNGGSQPhosphoSitePlus
T374GFNIStPRGIPPhosphoSitePlus
T503SDSPQtRTASGPhosphoSitePlus
S252NAARIsEKRKEPhosphoSitePlus; HPRD
T479PLPRGtPPPVFPhosphoSitePlus; HPRD; phosphoELM
S695SLLKNsPRNQQPhosphoSitePlus; HPRD
S597EAGHAsSPDSEPhosphoSitePlus; HPRD; phosphoELM
T485PPPVFtPPLPKPhosphoSitePlus; HPRD; phosphoELM
T648LFPADtSPSTAPhosphoSitePlus; HPRD
S424SSSHSsPGSPKPhosphoSitePlus; HPRD
Y685ESTGMyLRIRSPhosphoSitePlus
T496GTPPLtPSDSPPhosphoSitePlus; HPRD; phosphoELM
S649FPADTsPSTATPhosphoSitePlus; HPRD
T342DGKDGtDGETEPhosphoSitePlus

Dephosphorylation site
ZCHC8_HUMAN do not have dephosphorylation site.

Mutation site
ZCHC8_HUMAN do not have mutation site.

Differential expressed protein
ZCHC8_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZCHC8_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK7_HUMANZCHC8_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANZCHC8_HUMANkinase -> substrateRobert H Newman (2013)
SRPK2_HUMANZCHC8_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ZCHC8_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0000398mRNA splicing, via spliceosomeICbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0071013catalytic step 2 spliceosomeIDAcellular_component


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