| UniProt/SwissProt ID: | ZCHC8_HUMAN |
| Description: | zinc finger, CCHC domain containing 8 [Source:HGNC Symbol;Acc:25265] |
| Location: | chr12 q24.31 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T88 | ILVNDtKLDGP | HPRD | |
| S658 | ATKIHsPIPDM | PhosphoSitePlus; HPRD; phosphoELM | |
| S373 | PGFNIsTPRGI | PhosphoSitePlus | |
| S498 | PPLTPsDSPQT | PhosphoSitePlus; HPRD | |
| T492 | PLPKGtPPLTP | PhosphoSitePlus; HPRD; phosphoELM | |
| Y258 | EKRKEyMDACG | PhosphoSitePlus | |
| S500 | LTPSDsPQTRT | PhosphoSitePlus; HPRD; phosphoELM | |
| Y336 | SGLALyDGKDG | PhosphoSitePlus | |
| S427 | HSSPGsPKKQK | PhosphoSitePlus | |
| S601 | ASSPDsEVTSL | PhosphoSitePlus; HPRD | |
| T88 | ILVNDtKLDGP | Herpes_BLRF2 | PhosphoSitePlus |
| S640 | ISNGGsQKLFP | PhosphoSitePlus; HPRD; phosphoELM | |
| S598 | AGHASsPDSEV | PhosphoSitePlus; HPRD; phosphoELM | |
| T652 | DTSPStATKIH | PhosphoSitePlus | |
| S636 | PNCDIsNGGSQ | PhosphoSitePlus | |
| T374 | GFNIStPRGIP | PhosphoSitePlus | |
| T503 | SDSPQtRTASG | PhosphoSitePlus | |
| S252 | NAARIsEKRKE | PhosphoSitePlus; HPRD | |
| T479 | PLPRGtPPPVF | PhosphoSitePlus; HPRD; phosphoELM | |
| S695 | SLLKNsPRNQQ | PhosphoSitePlus; HPRD | |
| S597 | EAGHAsSPDSE | PhosphoSitePlus; HPRD; phosphoELM | |
| T485 | PPPVFtPPLPK | PhosphoSitePlus; HPRD; phosphoELM | |
| T648 | LFPADtSPSTA | PhosphoSitePlus; HPRD | |
| S424 | SSSHSsPGSPK | PhosphoSitePlus; HPRD | |
| Y685 | ESTGMyLRIRS | PhosphoSitePlus | |
| T496 | GTPPLtPSDSP | PhosphoSitePlus; HPRD; phosphoELM | |
| S649 | FPADTsPSTAT | PhosphoSitePlus; HPRD | |
| T342 | DGKDGtDGETE | PhosphoSitePlus | |
| Dephosphorylation site |
| ZCHC8_HUMAN do not have dephosphorylation site. |
| Mutation site |
| ZCHC8_HUMAN do not have mutation site. |
| Differential expressed protein |
| ZCHC8_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZCHC8_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK7_HUMAN | ZCHC8_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PKN1_HUMAN | ZCHC8_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SRPK2_HUMAN | ZCHC8_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZCHC8_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0000398 | mRNA splicing, via spliceosome | IC | biological_process |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0071013 | catalytic step 2 spliceosome | IDA | cellular_component |