Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:VEGFA_HUMAN
Description:vascular endothelial growth factor A [Source:HGNC Symbol;Acc:12680]
Location:chr6 p21.1
Node attribute:ligand; PPI(source)

Phosphorylation site
VEGFA_HUMAN do not have phosphorylation site.

Dephosphorylation site
VEGFA_HUMAN do not have dephosphorylation site.

Mutation site
VEGFA_HUMAN do not have mutation site.

Differential expressed protein
VEGFA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
VEGFA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
VEGFA_HUMANNRP1_HUMANligand -> receptorHPMR
VEGFA_HUMANVGFR2_HUMANligand -> receptorHPMR
VEGFA_HUMANVGFR1_HUMANligand -> receptorHPMR
VEGFA_HUMANVGFR1_HUMANotherKEGG
VEGFA_HUMANVGFR2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04150mTOR signaling pathway
hsa05219Bladder cancer
hsa04060Cytokine-cytokine receptor interaction
hsa05200Pathways in cancer
hsa04370VEGF signaling pathway
hsa05323Rheumatoid arthritis
hsa05212Pancreatic cancer
hsa05211Renal cell carcinoma
hsa04510Focal adhesion

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043183vascular endothelial growth factor receptor 1 bindIPImolecular_function
GO:0006357regulation of transcription from RNA polymerase IIIMPbiological_process
GO:0060948cardiac vascular smooth muscle cell developmentISSbiological_process
GO:0042802identical protein bindingIPImolecular_function
GO:0031077post-embryonic camera-type eye developmentISSbiological_process
GO:0050840extracellular matrix bindingICmolecular_function
GO:0090190positive regulation of branching involved in ureteISSbiological_process
GO:0010628positive regulation of gene expressionIDAbiological_process
GO:0071542dopaminergic neuron differentiationISSbiological_process
GO:0002053positive regulation of mesenchymal cell proliferatISSbiological_process
GO:0051781positive regulation of cell divisionIEAbiological_process
GO:0008083growth factor activityISSmolecular_function
GO:0050927positive regulation of positive chemotaxisIDAbiological_process
GO:0033138positive regulation of peptidyl-serine phosphorylaIDAbiological_process
GO:0005578proteinaceous extracellular matrixNAScellular_component
GO:0045766positive regulation of angiogenesisIMPbiological_process
GO:0030335positive regulation of cell migrationIDAbiological_process
GO:0010595positive regulation of endothelial cell migrationIDAbiological_process
GO:0001968fibronectin bindingIDAmolecular_function
GO:0005172vascular endothelial growth factor receptor bindinIPImolecular_function
GO:0042803protein homodimerization activityISSmolecular_function
GO:0016020membraneIEAcellular_component
GO:0051894positive regulation of focal adhesion assemblyIDAbiological_process
GO:0036303lymph vessel morphogenesisISSbiological_process
GO:0008201heparin bindingIMPmolecular_function
GO:0048754branching morphogenesis of a tubeISSbiological_process
GO:0001570vasculogenesisTASbiological_process
GO:0043154negative regulation of cysteine-type endopeptidaseIDAbiological_process
GO:0043184vascular endothelial growth factor receptor 2 bindIPImolecular_function
GO:0061418regulation of transcription from RNA polymerase IITASbiological_process
GO:0005161platelet-derived growth factor receptor bindingIPImolecular_function
GO:0071456cellular response to hypoxiaIDAbiological_process
GO:0003151outflow tract morphogenesisISSbiological_process
GO:1901727positive regulation of histone deacetylase activitIDAbiological_process
GO:0001525angiogenesisIDAbiological_process
GO:0001541ovarian follicle developmentISSbiological_process
GO:0060319primitive erythrocyte differentiationISSbiological_process
GO:0060982coronary artery morphogenesisISSbiological_process
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0032147activation of protein kinase activityIDAbiological_process
GO:0002052positive regulation of neuroblast proliferationISSbiological_process
GO:0043117positive regulation of vascular permeabilityIDAbiological_process
GO:0002042cell migration involved in sprouting angiogenesisIDAbiological_process
GO:0001569patterning of blood vesselsISSbiological_process
GO:0090050positive regulation of cell migration involved in IDAbiological_process
GO:0030855epithelial cell differentiationISSbiological_process
GO:0033554cellular response to stressTASbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIDAbiological_process
GO:0043536positive regulation of blood vessel endothelial ceIDAbiological_process
GO:0046982protein heterodimerization activityIDAmolecular_function
GO:0060749mammary gland alveolus developmentISSbiological_process
GO:0061419positive regulation of transcription from RNA polyIMPbiological_process
GO:0030324lung developmentISSbiological_process
GO:0038033positive regulation of endothelial cell chemotaxisIDAbiological_process
GO:0042056chemoattractant activityIDAmolecular_function
GO:0048010vascular endothelial growth factor receptor signalIDAbiological_process
GO:0035767endothelial cell chemotaxisIDAbiological_process
GO:0003169coronary vein morphogenesisISSbiological_process
GO:0048593camera-type eye morphogenesisISSbiological_process
GO:0045785positive regulation of cell adhesionIDAbiological_process
GO:0001666response to hypoxiaIDAbiological_process
GO:0005125cytokine activityISSmolecular_function
GO:0030141secretory granuleIDAcellular_component
GO:0005576extracellular regionTAScellular_component
GO:0048739cardiac muscle fiber developmentISSbiological_process
GO:0031954positive regulation of protein autophosphorylationIDAbiological_process
GO:0008360regulation of cell shapeIDAbiological_process
GO:0048844artery morphogenesisISSbiological_process
GO:0043129surfactant homeostasisISSbiological_process
GO:0031093platelet alpha granule lumenTAScellular_component
GO:0001701in utero embryonic developmentISSbiological_process
GO:0030168platelet activationTASbiological_process
GO:0050930induction of positive chemotaxisNASbiological_process
GO:0030949positive regulation of vascular endothelial growthIDAbiological_process
GO:0060754positive regulation of mast cell chemotaxisIDAbiological_process
GO:0050679positive regulation of epithelial cell proliferatiISSbiological_process
GO:0048469cell maturationISSbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0001822kidney developmentISSbiological_process
GO:0042462eye photoreceptor cell developmentISSbiological_process
GO:0008284positive regulation of cell proliferationIDAbiological_process
GO:1900745positive regulation of p38MAPK cascadeIDAbiological_process
GO:0030225macrophage differentiationIDAbiological_process
GO:0003007heart morphogenesisISSbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0035924cellular response to vascular endothelial growth fIDAbiological_process
GO:0001938positive regulation of endothelial cell proliferatISSbiological_process
GO:0050918positive chemotaxisIDAbiological_process
GO:1900086positive regulation of peptidyl-tyrosine autophospIDAbiological_process
GO:0002575basophil chemotaxisIDAbiological_process
GO:0043406positive regulation of MAP kinase activityIDAbiological_process
GO:0002576platelet degranulationTASbiological_process
GO:0001934positive regulation of protein phosphorylationIDAbiological_process
GO:0051272positive regulation of cellular component movementIDAbiological_process
GO:0048018receptor agonist activityIPImolecular_function
GO:0007498mesoderm developmentISSbiological_process
GO:0007595lactationISSbiological_process
GO:0040007growthISSbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0043498cell surface bindingIDAmolecular_function
GO:0002092positive regulation of receptor internalizationIDAbiological_process
GO:0090037positive regulation of protein kinase C signaling IDAbiological_process
GO:0007399nervous system developmentTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005615extracellular spaceISScellular_component
GO:0032793positive regulation of CREB transcription factor aIDAbiological_process
GO:0030224monocyte differentiationIDAbiological_process
GO:0031334positive regulation of protein complex assemblyIDAbiological_process
GO:0002687positive regulation of leukocyte migrationTASbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0010740positive regulation of intracellular protein kinasIDAbiological_process
GO:0038091positive regulation of cell proliferation by VEGF-IDAbiological_process
GO:0043066negative regulation of apoptotic processIMPbiological_process