Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:VASP_HUMAN
Description:vasodilator-stimulated phosphoprotein [Source:HGNC Symbol;Acc:12652]
Location:chr19 q13.32
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S239KLRKVsKQEEAPRKACAHPRD; SysPTM
Y39SRVQIyHNPTAHPRD; phosphoELM; RegPhos
S157IERRVsNAGGPPRKG1HPRD
S239KLRKVsKQEEAPKG_groupRegPhos; SysPTM
S157IERRVsNAGGPPKG/cGK_groupphosphoELM
S239KLRKVsKQEEAPKA_groupphosphoELM; RegPhos; SysPTM
T278RRRKAtQVGEKPKACaRegPhos
T278RRRKAtQVGEKPKG1RegPhos
T316EKNSTtLPRMKPhosphoSitePlus; HPRD; SysPTM
S322LPRMKsSSSVTPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
T284QVGEKtPKDESPhosphoSitePlus; HPRD
T278RRRKAtQVGEKPhosphoSitePlus
S157IERRVsNAGGPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S157IERRVsNAGGPPKACaRegPhos
Y341PSSSDySDLQRVASP_tetraPhosphoSitePlus
T327SSSSVtTSETQPhosphoSitePlus; HPRD
T331VTTSEtQPCTPPhosphoSitePlus
S157IERRVsNAGGPROCK1RegPhos
Y39SRVQIyHNPTAWH1PhosphoSitePlus
T278RRRKAtQVGEKPKG/cGK_groupphosphoELM
S324RMKSSsSVTTSPhosphoSitePlus; HPRD
S239KLRKVsKQEEAPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
T278RRRKAtQVGEKPRKACAHPRD
S157IERRVsNAGGPPKG1RegPhos
S239KLRKVsKQEEAPRKG1HPRD; SysPTM
T278RRRKAtQVGEKPKA_groupphosphoELM; RegPhos
T315WEKNStTLPRMphosphoELM
S157IERRVsNAGGPPKC_groupRegPhos
T328SSSVTtSETQPPhosphoSitePlus
S157IERRVsNAGGPPKA_groupphosphoELM; RegPhos
S325MKSSSsVTTSEPhosphoSitePlus; HPRD
T335ETQPCtPSSSDPhosphoSitePlus
S157IERRVsNAGGPPKG_groupRegPhos
S239KLRKVsKQEEAPKG1RegPhos; SysPTM
T249ASGGPtAPKAEPhosphoSitePlus; HPRD
S337QPCTPsSSDYSPhosphoSitePlus
S239KLRKVsKQEEAPKG/cGK_groupphosphoELM; SysPTM
T278RRRKAtQVGEKPRKG1HPRD
S157IERRVsNAGGPPRKACAHPRD
T43IYHNPtANSFRWH1PhosphoSitePlus
T278RRRKAtQVGEKPKG_groupRegPhos
S239KLRKVsKQEEAPKACaRegPhos; SysPTM
Y16ATVMLyDDGNKWH1PhosphoSitePlus
S323PRMKSsSSVTTPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S314PWEKNsTTLPRPhosphoSitePlus

Dephosphorylation site
VASP_HUMAN do not have dephosphorylation site.

Mutation site
VASP_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000245932Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
SiteMotifPeptideCancer namePubmedSource
Y39WH1AFSRVQIyHNPTANScholangiocellular carcinoma21253578PhosphoSitePlus

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANVASP_HUMANkinase -> substrateRegPhos
ROCK1_HUMANVASP_HUMANkinase -> substrateRegPhos
KPCA_HUMANVASP_HUMANkinase -> substrateHPRD
KGP1_HUMANVASP_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04510Focal adhesion
hsa04670Leukocyte transendothelial migration
hsa04666Fc gamma R-mediated phagocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneIDAcellular_component
GO:0034329cell junction assemblyTASbiological_process
GO:0007411axon guidanceIEAbiological_process
GO:0005856cytoskeletonIEAcellular_component
GO:0001843neural tube closureIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0031258lamellipodium membraneIEAcellular_component
GO:0003779actin bindingIEAmolecular_function
GO:0051289protein homotetramerizationIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0005522profilin bindingIPImolecular_function
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0005925focal adhesionIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0030027lamellipodiumIEAcellular_component
GO:0007411axon guidanceTASbiological_process
GO:0015629actin cytoskeletonTAScellular_component
GO:0030175filopodiumIEAcellular_component
GO:0030036actin cytoskeleton organizationIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0031527filopodium membraneIEAcellular_component
GO:0008154actin polymerization or depolymerizationIEAbiological_process
GO:0005925focal adhesionIEAcellular_component
GO:0017124SH3 domain bindingIEAmolecular_function


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