Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UBC9_HUMAN
Description:ubiquitin-conjugating enzyme E2I [Source:HGNC Symbol;Acc:12485]
Location:chr16 p13.3
Node attribute:substrate; sumoylation(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S2____MsGIALSPhosphoSitePlus
T35KNPDGtMNLMNUQ_conPhosphoSitePlus
S71DDYPSsPPKCKUQ_conPhosphoSitePlus
S2IALSHPRD
S70KDDYPsSPPKCUQ_conPhosphoSitePlus

Dephosphorylation site
UBC9_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000385009W103CCOSMICHead and Neck Cancer21798893
ENSP00000380649W103CCOSMICHead and Neck Cancer21798893
ENSP00000457064W103CCOSMICHead and Neck Cancer21798893
ENSP00000384568W103CCOSMICHead and Neck Cancer21798893
ENSP00000348056W103CCOSMICHead and Neck Cancer21798893
ENSP00000380650W103CCOSMICHead and Neck Cancer21798893
ENSP00000324897W103CCOSMICHead and Neck Cancer21798893

Differential expressed protein
UBC9_HUMAN is not differential expressed protein.

Hyperphosphorylation site
UBC9_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MP2K4_HUMANUBC9_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANUBC9_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANUBC9_HUMANkinase -> substrateRobert H Newman (2013)
DYRK2_HUMANUBC9_HUMANkinase -> substrateRobert H Newman (2013)
UBC9_HUMANANDR_HUMANsumoylationNetPath

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03013RNA transport
hsa04064NF-kappa B signaling pathway
hsa04120Ubiquitin mediated proteolysis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIDAcellular_component
GO:0000795synaptonemal complexTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0008022protein C-terminus bindingIEAmolecular_function
GO:0045202synapseIEAcellular_component
GO:0033145positive regulation of intracellular steroid hormoIEAbiological_process
GO:0007059chromosome segregationIEAbiological_process
GO:0008134transcription factor bindingIPImolecular_function
GO:0043425bHLH transcription factor bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0051301cell divisionIEAbiological_process
GO:0019899enzyme bindingIPImolecular_function
GO:0001650fibrillar centerIEAcellular_component
GO:0043398HLH domain bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0016604nuclear bodyIEAcellular_component
GO:0006511ubiquitin-dependent protein catabolic processTASbiological_process
GO:0016605PML bodyIDAcellular_component
GO:0043161proteasomal ubiquitin-dependent protein catabolic IEAbiological_process
GO:0030425dendriteIEAcellular_component
GO:0016881acid-amino acid ligase activityIEAmolecular_function
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0010469regulation of receptor activityIEAbiological_process
GO:0071535RING-like zinc finger domain bindingIPImolecular_function
GO:0006464cellular protein modification processTASbiological_process
GO:0004842ubiquitin-protein ligase activityIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0007067mitosisIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0016567protein ubiquitinationIEAbiological_process
GO:0051091positive regulation of sequence-specific DNA bindiIEAbiological_process
GO:0019789SUMO ligase activityIEAmolecular_function
GO:0016925protein sumoylationIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIMPbiological_process
GO:0019048virus-host interactionIEAbiological_process


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