| UniProt/SwissProt ID: | TCAM2_HUMAN |
| Description: | toll-like receptor adaptor molecule 2 [Source:HGNC Symbol;Acc:21354] |
| Location: | chr5 q22.3 |
| Node attribute: | PPI(source); PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S14 | NSCPLsLSWGK | PhosphoSitePlus | |
| S16 | CPLSLsWGKRH | PKCe | RegPhos |
| S16 | CPLSLsWGKRH | PhosphoSitePlus | |
| Dephosphorylation site |
| TCAM2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TCAM2_HUMAN do not have mutation site. |
| Differential expressed protein |
| TCAM2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TCAM2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TCAM2_HUMAN | TCAM1_HUMAN | other | KEGG |
| TLR4_HUMAN | TCAM2_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04064 | NF-kappa B signaling pathway |
| hsa05133 | Pertussis |
| hsa04620 | Toll-like receptor signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0034138 | toll-like receptor 3 signaling pathway | TAS | biological_process |
| GO:0035666 | TRIF-dependent toll-like receptor signaling pathwa | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB c | IMP | biological_process |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0010008 | endosome membrane | TAS | cellular_component |
| GO:0004871 | signal transducer activity | IMP | molecular_function |
| GO:0007249 | I-kappaB kinase/NF-kappaB cascade | TAS | biological_process |
| GO:0034142 | toll-like receptor 4 signaling pathway | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0008063 | Toll signaling pathway | TAS | biological_process |
| GO:0006954 | inflammatory response | IEA | biological_process |
| GO:0045087 | innate immune response | TAS | biological_process |