| UniProt/SwissProt ID: | STAP1_HUMAN |
| Description: | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:24133] |
| Location: | chr4 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y57 | TTLFFyTDKKS | PH | PhosphoSitePlus |
| Y27 | TALPLyFEGFL | PhosphoSitePlus | |
| T22 | ERLKItALPLY | PhosphoSitePlus | |
| S196 | LQKNPsLGNMI | SH2 | PhosphoSitePlus; SysPTM |
| Y45 | REYEHyWTELR | PH | PhosphoSitePlus |
| Y42 | SGYREyEHYWT | PH | PhosphoSitePlus |
| S196 | LQKNPsLGNMI | phosphoELM; SysPTM | |
| Dephosphorylation site |
| STAP1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000379527 | I71K | COSMIC | Hepatocellular Carcinoma | 21822264 |
| Differential expressed protein |
| STAP1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STAP1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TEC_HUMAN | STAP1_HUMAN | kinase -> substrate | NetPath |
| FAK2_HUMAN | STAP1_HUMAN | kinase -> substrate | NetPath |
| KIT_HUMAN | STAP1_HUMAN | kinase -> substrate | NetPath |
| Function Annotation |
| KEGG Pathway |
| STAP1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0043234 | protein complex | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0006944 | cellular membrane fusion | TAS | biological_process |
| GO:0007169 | transmembrane receptor protein tyrosine kinase sig | IEA | biological_process |
| GO:0006886 | intracellular protein transport | TAS | biological_process |
| GO:0005739 | mitochondrion | IDA | cellular_component |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0005070 | SH3/SH2 adaptor activity | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005543 | phospholipid binding | IEA | molecular_function |