| UniProt/SwissProt ID: | SRSF4_HUMAN |
| Description: | serine/arginine-rich splicing factor 4 [Source:HGNC Symbol;Acc:10786] |
| Location: | chr1 p35.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S302 | KSKSRsRSQER | PhosphoSitePlus; HPRD; phosphoELM | |
| S188 | RSYSRsRSHSR | PhosphoSitePlus; phosphoELM | |
| S113 | VENLSsRCSWQ | HPRD; phosphoELM | |
| Y53 | ADDAVyELNGK | phosphoELM | |
| S458 | NLPSEsRSRSK | PhosphoSitePlus; HPRD; phosphoELM | |
| S255 | PSKEKsRSRSH | PhosphoSitePlus; HPRD; phosphoELM | |
| S456 | KPNLPsESRSR | PhosphoSitePlus; HPRD | |
| Y53 | ADDAVyELNGK | RRM_1 | PhosphoSitePlus |
| S368 | ESRSRsRSRSK | PhosphoSitePlus | |
| S192 | RSRSHsRSRSR | PhosphoSitePlus | |
| S431 | EGRGEsENAGT | PhosphoSitePlus; HPRD; phosphoELM | |
| S442 | NQETRsRSRSN | phosphoELM | |
| S288 | VGKPKsRSPSR | PhosphoSitePlus; HPRD | |
| S448 | RSRSNsKSKPN | PhosphoSitePlus; HPRD; phosphoELM | |
| S364 | RSREEsRSRSR | PhosphoSitePlus | |
| S318 | KRGSVsRGRSQ | PhosphoSitePlus | |
| S265 | HSAGKsRSKSK | PhosphoSitePlus | |
| S190 | YSRSRsHSRSR | PhosphoSitePlus | |
| S462 | ESRSRsKSASK | PhosphoSitePlus; HPRD; phosphoELM | |
| S360 | KGRKRsREESR | PhosphoSitePlus | |
| S300 | KSKSKsRSRSQ | PhosphoSitePlus; HPRD; phosphoELM | |
| T436 | SENAGtNQETR | HPRD | |
| S112 | IVENLsSRCSW | RRM_1 | PhosphoSitePlus |
| S322 | VSRGRsQEKSL | PhosphoSitePlus; HPRD; phosphoELM | |
| S113 | VENLSsRCSWQ | RRM_1 | PhosphoSitePlus |
| T440 | GTNQEtRSRSR | PhosphoSitePlus; HPRD; phosphoELM | |
| S238 | RSRSQsRSRSK | PhosphoSitePlus | |
| S186 | RRRSYsRSRSH | PhosphoSitePlus | |
| S292 | KSRSPsRHKSK | PhosphoSitePlus; HPRD | |
| S316 | EEKRGsVSRGR | PhosphoSitePlus; HPRD; phosphoELM | |
| S257 | KEKSRsRSHSA | PhosphoSitePlus | |
| S460 | PSESRsRSKSA | PhosphoSitePlus; HPRD; phosphoELM | |
| S304 | KSRSRsQERRV | PhosphoSitePlus; HPRD; phosphoELM | |
| S222 | KSRSRsRSGSR | PhosphoSitePlus; HPRD; phosphoELM | |
| S116 | LSSRCsWQDLK | RRM_1 | PhosphoSitePlus |
| S259 | KSRSRsHSAGK | PhosphoSitePlus | |
| S232 | RSRSKsRSRSQ | PhosphoSitePlus | |
| S78 | PRRDGsYGSGR | PhosphoSitePlus; HPRD | |
| S290 | KPKSRsPSRHK | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| SRSF4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| SRSF4_HUMAN do not have mutation site. |
| Differential expressed protein |
| SRSF4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SRSF4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PK3C3_HUMAN | SRSF4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| M3K7_HUMAN | SRSF4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| SRSF4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031124 | mRNA 3'-end processing | TAS | biological_process |
| GO:0048025 | negative regulation of mRNA splicing, via spliceos | IDA | biological_process |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0016607 | nuclear speck | IEA | cellular_component |
| GO:0006369 | termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0006406 | mRNA export from nucleus | TAS | biological_process |
| GO:0010467 | gene expression | TAS | biological_process |
| GO:0000166 | nucleotide binding | IEA | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0000398 | mRNA splicing, via spliceosome | TAS | biological_process |
| GO:0006397 | mRNA processing | TAS | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | biological_process |