Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SRSF4_HUMAN
Description:serine/arginine-rich splicing factor 4 [Source:HGNC Symbol;Acc:10786]
Location:chr1 p35.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S302KSKSRsRSQERPhosphoSitePlus; HPRD; phosphoELM
S188RSYSRsRSHSRPhosphoSitePlus; phosphoELM
S113VENLSsRCSWQHPRD; phosphoELM
Y53ADDAVyELNGKphosphoELM
S458NLPSEsRSRSKPhosphoSitePlus; HPRD; phosphoELM
S255PSKEKsRSRSHPhosphoSitePlus; HPRD; phosphoELM
S456KPNLPsESRSRPhosphoSitePlus; HPRD
Y53ADDAVyELNGKRRM_1PhosphoSitePlus
S368ESRSRsRSRSKPhosphoSitePlus
S192RSRSHsRSRSRPhosphoSitePlus
S431EGRGEsENAGTPhosphoSitePlus; HPRD; phosphoELM
S442NQETRsRSRSNphosphoELM
S288VGKPKsRSPSRPhosphoSitePlus; HPRD
S448RSRSNsKSKPNPhosphoSitePlus; HPRD; phosphoELM
S364RSREEsRSRSRPhosphoSitePlus
S318KRGSVsRGRSQPhosphoSitePlus
S265HSAGKsRSKSKPhosphoSitePlus
S190YSRSRsHSRSRPhosphoSitePlus
S462ESRSRsKSASKPhosphoSitePlus; HPRD; phosphoELM
S360KGRKRsREESRPhosphoSitePlus
S300KSKSKsRSRSQPhosphoSitePlus; HPRD; phosphoELM
T436SENAGtNQETRHPRD
S112IVENLsSRCSWRRM_1PhosphoSitePlus
S322VSRGRsQEKSLPhosphoSitePlus; HPRD; phosphoELM
S113VENLSsRCSWQRRM_1PhosphoSitePlus
T440GTNQEtRSRSRPhosphoSitePlus; HPRD; phosphoELM
S238RSRSQsRSRSKPhosphoSitePlus
S186RRRSYsRSRSHPhosphoSitePlus
S292KSRSPsRHKSKPhosphoSitePlus; HPRD
S316EEKRGsVSRGRPhosphoSitePlus; HPRD; phosphoELM
S257KEKSRsRSHSAPhosphoSitePlus
S460PSESRsRSKSAPhosphoSitePlus; HPRD; phosphoELM
S304KSRSRsQERRVPhosphoSitePlus; HPRD; phosphoELM
S222KSRSRsRSGSRPhosphoSitePlus; HPRD; phosphoELM
S116LSSRCsWQDLKRRM_1PhosphoSitePlus
S259KSRSRsHSAGKPhosphoSitePlus
S232RSRSKsRSRSQPhosphoSitePlus
S78PRRDGsYGSGRPhosphoSitePlus; HPRD
S290KPKSRsPSRHKPhosphoSitePlus; HPRD

Dephosphorylation site
SRSF4_HUMAN do not have dephosphorylation site.

Mutation site
SRSF4_HUMAN do not have mutation site.

Differential expressed protein
SRSF4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SRSF4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PK3C3_HUMANSRSF4_HUMANkinase -> substrateRobert H Newman (2013)
M3K7_HUMANSRSF4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SRSF4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031124mRNA 3'-end processingTASbiological_process
GO:0048025negative regulation of mRNA splicing, via spliceosIDAbiological_process
GO:0005634nucleusTAScellular_component
GO:0016607nuclear speckIEAcellular_component
GO:0006369termination of RNA polymerase II transcriptionTASbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0006406mRNA export from nucleusTASbiological_process
GO:0010467gene expressionTASbiological_process
GO:0000166nucleotide bindingIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0008380RNA splicingTASbiological_process
GO:0000398mRNA splicing, via spliceosomeTASbiological_process
GO:0006397mRNA processingTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0000375RNA splicing, via transesterification reactionsTASbiological_process


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